| guanylate cyclase | <enzyme> That is responsible for catalysing the synthesis of guanosine 3', 5' cyclic monophosphate from guanosine 5' triphosphate (cyclic GMP cGMP) is used as a second messenger in heart muscle and photoreceptor cells). Plasma membrane form of guanylate cyclase is Integral membrane proteins with an extracellular receptor for peptide hormones, a transmembrane domain, a protein kinase like domain and a guanylate cyclase domain. Examples: sea urchin receptors for speract and resact and atrial natriuretic peptide receptors. Two soluble forms of guanylate cyclase are also known they are heterodimers of highly related subunits, 70-80 kD. (18 Nov 1997) |
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| guanylate kinase | <enzyme> Erythrocyte protein p55 is a sequenced membrane-bound guanylate kinase Registry number: EC 2.7.4.8 Synonym: GMP kinase, guanylate kinase 1, erythrocyte protein p55, chapsyn-110, magi-1 protein, maguk enzyme, membrane-associated guanylate kinase (26 Jun 1999) |