| Groenouw's corneal dystrophy | A granular type of corneal dystrophy, with autosomal dominant inheritance, a macular type of corneal dystrophy, with autosomal recessive inheritance. (05 Mar 2000) |
|---|---|
| ring-like corneal dystrophy | Thread-like opacities of the anterior corneal stroma, with acute, painful onset followed by decreased vision; autosomal dominant inheritance. (05 Mar 2000) |
| corneal dystrophy | Central corneal opacification, usually bilateral, symmetrical, and often autosomal recessive, involving predominantly epithelial, stromal, or endothelial layers, often in a typical pattern. (05 Mar 2000) |
| juvenile epithelial corneal dystrophy | Epithelial dystrophy characterised by progressive cysts and opacities of the corneal epithelium, with onset in infancy. Inheritance: autosomal dominant with incomplete penetrance. Synonym: Meesman dystrophy. (22 Sep 2002) |
| lattice corneal dystrophy | A corneal dystrophy due to localised accumulation of amyloid in a reticular pattern; manifest at puberty and progressing slowly until eventually useful vision is lost; autosomal dominant inheritance. (05 Mar 2000) |
| Paneth's granular cells | Cell's, located at the base of intestinal glands of the small intestine, which contain large acidophilic refractile granules and may produce lysozyme. Synonym: Davidoff's cells. (05 Mar 2000) |
| granular | 1. Composed of or resembling granules or granulations. 2. Particles with strong affinity for nuclear stains, seen in many bacterial species. (05 Mar 2000) |
| granular cast | A relatively dark, dense urinary cast of coarsely or finely particulate cellular debris and other proteinaceous material, frequently seen in chronic renal disease but also in the recovery phase of acute renal failure. See: waxy cast. (05 Mar 2000) |
| granular cell tumour | Unusual tumour affecting any site of the body, but most often encountered in the head and neck. Considerable debate has surrounded the histogenesis of this neoplasm; however, it is considered to be a myoblastoma of, usually, a benign nature. It affects women more often than men. When it develops beneath the epidermis or mucous membrane, it can lead to proliferation of the squamous cells and mimic squamous cell carcinoma. (12 Dec 1998) |
| granular component of nucleolus | Area of nucleolus that appears granular in the electron microscope and contains 15nm diameter particles that are maturing ribosomes. In contrast to the pale staining and fibrillar areas. (18 Nov 1997) |
| granular conjunctivitis | A chronic infection of the conjunctiva due to Chlamydia trachomatis, characterised by conjunctival follicles and subsequent cicatrization. See: trachoma. Synonym: granular conjunctivitis. (05 Mar 2000) |
| granular cortex | See: cerebral cortex. (05 Mar 2000) |
| granular degeneration | Swelling of cells due to injury to the membranes affecting ionic transfer; causes an accumulation of intracellular water. Synonym: albuminous swelling, granular degeneration, hydropic degeneration, parenchymatous degeneration. (05 Mar 2000) |
| granular endoplasmic reticulum | Endoplasmic reticulum in which ribosomal granules are applied to the cytoplasmic surface of the cisternae; involved in the synthesis and secretion of protein via membrane-bound vesicles to the extracellular space. Synonym: chromidial substance, ergastoplasm, rough-surfaced endoplasmic reticulum. (05 Mar 2000) |
| granular kidney | A kidney in which fairly uniform, diffusely and evenly situated foci of scarring of the interstitial tissue of the cortex (and sometimes scarring of glomeruli), and the associated slight degree of bulging of groups of dilated tubules, leads to the development of a minutely bosselated surface; such kidney's are seen in arteriolar nephrosclerosis or chronic glomerulonephritis. Synonym: sclerotic kidney. (05 Mar 2000) |