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glycin <physiology> Same as Glycocoll.
Origin: Gr. Glykys sweet.
Source: Websters Dictionary
(01 Mar 1998)
glycinamide ribonucleotide An intermediate in purine biosynthesis, in which the amide N of glycineamide is linked to the C-1 of a ribosyl moiety.
(05 Mar 2000)
glycinate 1. A salt of glycine.
2. Glycine anion.
(05 Mar 2000)
glycine <amino acid, physiology> The simplest amino acid. It is a common residue in proteins, especially collagen and elastin and is not optically active.
It is also a major inhibitory neurotransmitter in spinal cord and brainstem of vertebrate central nervous system.
(18 Nov 1997)
glycine acyltransferase <enzyme> An enzyme catalyzing the reversible transfer of an acyl group from acyl-CoA to glycine, producing free coenzyme A and N-acylglycine; a step in a detoxification pathway.
(05 Mar 2000)
glycine agents Substances used for their pharmacological actions on glycinergic systems. Glycinergic agents include agonists, antagonists, degradation or uptake inhibitors, depleters, precursors, and modulators of receptor function.
(12 Dec 1998)
glycine amidinotransferase <enzyme> An enzyme catalyzing the transfer of an amidine group from l-arginine to glycine, forming guanidinoacetate and l-ornithine; an important reaction in creatine synthesis; it can also act on canavanine.
Synonym: glycine transamidinase.
(05 Mar 2000)
glycine betaine <chemical> A derivative of glycine characterised by high water solubility. Can function as an osmotic agent in plant tissues.
See: biogenic amines.
(18 Nov 1997)
glycine cleavage complex A complex of several proteins that catalyze the reversible reaction of glycine with tetrahydrofolate to produce CO2, NH3, and N5,N10-methylenetetrahydrofolate; a deficiency of this enzyme (or one of its subunits) will result in nonketotic hyperglycinaemia.
Synonym: glycine synthase.
(05 Mar 2000)
glycine dehydrogenase Enzymes that catalyze the conversion of glycine to glyoxylate and ammonia, using either NAD+ or ferricytochrome c.
(05 Mar 2000)
glycine hydroxymethyltransferase <enzyme> A pyridoxal phosphate enzyme that catalyses the reaction of glycine and 5,10-methylene-tetrahydrofolate to form serine. It also catalyses the reaction of glycine with acetaldehyde to form l-threonine.
Chemical name: 5,10-Methylenetetrahydrofolate:glycine hydroxymethyltransferase
Registry number: EC 2.1.2.1
(12 Dec 1998)
glycine methyltransferase <enzyme> Liver protein sediments in the 4-s region of sucrose gradients; binds to benzo(a)pyrene and to folate
Registry number: EC 2.1.1.20
Synonym: glycine n-methyltransferase, carcinogen-binding protein, 4s carcinogen-binding protein, 4-s carcinogen-binding protein, 4s polycylic aromatic hydrocarbon-binding protein, 4s pah-binding protein, pah-binding protein
(26 Jun 1999)
glycine receptor <physiology> Chloride channel forming receptor. One of a family of neurotransmitter receptors with fast intrinsic ion channels.
See: amino acid receptors.
(18 Nov 1997)
glycine reductase <enzyme> Glycine is reductively deaminated to acetate and ammonia by a complex requiring a dithiol and synthesizing ATP
Registry number: EC 1.4.1.-
(26 Jun 1999)
glycine synthase A complex of several proteins that catalyze the reversible reaction of glycine with tetrahydrofolate to produce CO2, NH3, and N5,N10-methylenetetrahydrofolate; a deficiency of this enzyme (or one of its subunits) will result in nonketotic hyperglycinaemia.
Synonym: glycine synthase.
(05 Mar 2000)
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