| UGT | uridine diphosphate-glucuronosyltransferase; urogenital tract; urogenital tuberculosis |
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| GT | UDP)-glucuronosyltransferase |
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| UGT | Uridine diphosphate glucuronosyltransferase |
| UGT | Uridine diphospho-glucuronosyltransferase |
| glucuronosyltransferase | <enzyme> A family of enzymes accepting a wide range of substrates, including phenols, alcohols, amines, and fatty acids. They function as drug-metabolizing enzymes that catalyze the conjugation of udpglucuronic acid to a variety of endogenous and exogenous compounds. Chemical name: UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific) Registry number: EC 2.4.1.17 (12 Dec 1998) |
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| bilirubin glucuronoside glucuronosyltransferase | <enzyme> Conjugates one or two glucuronic acid molecules to the carboxyl groups of the propionate side chains of bilirubin thereby removing free bilirubin from the body; ugt1.4 is the minor human bilirubin udp-glucuronosyltransferase (ugt) Registry number: EC 2.4.1.95 Synonym: bilirubin glucuronyl transferase, bilirubin glucuronyltransferase, bilirubin udp-glucuronosyltransferase, ugt1.4 (26 Jun 1999) |
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| phenol glucuronosyltransferase | <enzyme> Also catalyses the glucuronidation of 1-naphthol, 4-methylumbelliferone, 4-nitrophenol and related cpds; encoded by ugt1 complex Registry number: EC 2.4.1.- Synonym: phenol gcstransferase, phenol udp-glucuronosyltransferase, ugt1a1, rat, 1-naphthol udp-glucuronosyltransferase (26 Jun 1999) |
| cytosine-UDP-glucuronosyltransferase | <enzyme> Catalyses the formation of cytosylglucuronic acid from udp-glucuronic acid and cytosine in the formation of blasticidin s; isolated from streptomyces griseochromogenes Registry number: EC 2.4.1.- Synonym: cytosylglucuronic acid synthase, cga synthase (26 Jun 1999) |
| UDPglucuronate-bilirubinglucuronoside glucuronosyltransferase | Hepatic transferases that catalyze the transfer of the glucuronic moiety of UDP-glucuronic acid to bilirubin or bilirubin glucuronide, thus producing UDP and either bilirubin-glucoronoside or bilirubin bisglucuronoside, respectively; these bile conjugates are then secreted into the bile. Synonym: UDPglucuronate-bilirubinglucuronoside glucuronosyltransferase. (05 Mar 2000) |
| UDPglucuronate-bilirubin glucuronosyltransferase | Hepatic transferases that catalyze the transfer of the glucuronic moiety of UDP-glucuronic acid to bilirubin or bilirubin glucuronide, thus producing UDP and either bilirubin-glucoronoside or bilirubin bisglucuronoside, respectively; these bile conjugates are then secreted into the bile. Synonym: UDPglucuronate-bilirubinglucuronoside glucuronosyltransferase. (05 Mar 2000) |
Synonyms : 17 beta-Hydroxysteroid UDP-Glucuronosyltransferase, 4-Nitrophenol-UDP-Glucuronosyltransferase, 7-Hydroxycoumarin UDP Glucuronyltransferase, Androsterone UDP-Glucuronosyltransferase, Bilirubin UDP-Glucuronyltransferase, Estrogen UDP-Glucuronosyltransferase
| glucuronosyltransferase |
[EC 2.4.1.17] an enzyme of the transferase class that catalyzes the transfer of a glucuronate moiety from UDPglucuronate to an acceptor to form a glucuronide conjugate. The reaction occurs with a wide range of substrates and is important in the conversion of bilirubin to its more soluble glucuronide conjugates, which are then secreted into the bile. Deficiency of the enzyme, an autosomal recessive trait, results in Crigler-Najjar syndrome.
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