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glucose oxidase [EC 1.1.3.4] an enzyme of the oxidoreductase class that catalyzes the oxidation of glucose, reducing oxygen to hydrogen peroxide. It is a flavoprotein, containing FAD, and is highly specific for β-D-glucose. The enzyme is produced by Penicillium notatum and other fungi and has antibacterial activity in the presence of glucose and oxygen because of the hydrogen peroxide produced. It is used to estimate glucose concentration in blood or urine samples through the formation of colored dyes by the hydrogen peroxide.
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