| glomerulonephritis | <nephrology> A variety of nephritis characterised by inflammation of the capillary loops in the glomeruli of the kidney. It occurs in acute, subacute and chronic forms and may be secondary to haemolytic streptococcal infection. Evidence also supports possible immune or autoimmune mechanisms. (18 Nov 1997) |
|---|---|
| glomerulonephritis, IgA | Chronic form of glomerulonephritis characterised by recurring haematuria with only slight proteinuria and by deposits of IgA immunoglobulin in the mesangial areas of the renal glomeruli. It usually occurs in young males. (12 Dec 1998) |
| glomerulonephritis, membranoproliferative | Chronic glomerulonephritis characterised histologically by proliferation of mesangial cells, increase in the mesangial matrix, and a thickening of the glomerular capillary walls. The wall thickening is sometimes said to be a result of the interposition of mesangial cytoplasm or matrix between the basement membrane and the endothelium of the capillary wall. It is often divided into types I and II, and sometimes III. Pathogenesis is not well understood, but some types are thought to involve the immune system, with the complement system, in particular, being implicated. (12 Dec 1998) |
| glomerulonephritis, membranous | A disease of the glomerulus manifested clinically by proteinuria, and sometimes by other features of the nephrotic syndrome. It is histologically characterised by deposits in the glomerular capillary wall between the epithelial cell and the basement membrane and a thickening of the membrane. Also characteristic are outward projections of the membrane between the epithelial deposits in the form of "spikes". There is some agreement that the deposits are antigen-antibody complexes. (12 Dec 1998) |
| glomerulopathy | Glomerular disease of any type. Origin: Glomerulus + G. Pathos, suffering (05 Mar 2000) |
| glomerulosa cell | A cell of the zona glomerulosa of the adrenal cortex that is the source of aldosterone; the cell's are arranged in spherical or oval groups. (05 Mar 2000) |
| glomerulosclerosis | Hyaline deposits or scarring within the renal glomeruli, a degenerative process occurring in association with renal arteriosclerosis or diabetes. Synonym: glomerular sclerosis. Origin: Glomerulus + G. Sklerosis, hardness (05 Mar 2000) |
| glomerulosclerosis, focal | Glomerular disease characterised by focal and segmental areas of glomerular sclerosis, usually commencing in the juxtamedullary glomeruli and gradually spreading to involve other parts of the kidney, with eventual kidney failure. (12 Dec 1998) |
| glomerulose | <nephrology> Pertaining to or of the nature of a glomerulus, especially a renal glomerulus. (14 Oct 1997) |