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glomerular filtration rate <nephrology> Measure of the kidneys' ability to filter and remove waste products.
(09 Oct 1997)
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gel filtration <molecular biology> An important method for separating molecules according to molecular size by percolating the solution through beads of solvent permeated polymer that has pores of similar size to the solvent molecules. Unlike a continous filter that retards flow according to molecular size, separation is achieved because molecules that can enter the beads take a longer path (i.e. Are retarded) than those that cannot. Typical gels for protein separation are made from polyacrylamide or from flexible (Sephadex) or rigid (agarose, Sepharose) sugar polymers. The size separation range is determined by the degree of cross linking of the gel.
(05 May 1997)
gel filtration chromatography See: gel filtration.
(05 Mar 2000)
filtration The passage of a liquid through a filter, accomplished by gravity, pressure or vacuum (suction).
(18 Nov 1997)
filtration angle The acute angle between the iris and the cornea at the periphery of the anterior chamber of the eye.
Synonym: angulus iridocornealis, angle of iris, angulus iridis, filtration angle.
(05 Mar 2000)
filtration coefficient A measure of a membrane's permeability to water; specifically, the volume of fluid filtered in unit time through a unit area of membrane per unit pressure difference, taking into account both hydraulic and osmotic pressures.
(05 Mar 2000)
filtration fraction The fraction of the plasma entering the kidney that filters into the lumen of the renal tubules, determined by dividing the glomerular filtration rate by the renal plasma flow; normally, it is around 0.17.
(05 Mar 2000)
filtration slits The intercellular clefts between the interdigitating pedicels of podocytes; they are part of the filtration barrier of renal corpuscles.
Synonym: filtration slits.
(05 Mar 2000)
filtration space
afferent glomerular arteriole A branch of an interlobular artery of the kidney that conveys blood to the glomerulus.
Synonym: arteriola glomerularis afferens, vas afferens, afferent vessel.
(05 Mar 2000)
anti-glomerular basement membrane disease Glomerulonephritis, usually of a generalised proliferative crescent-forming histologic type with a rapidly progressive course, marked by circulating anti-gbm antibodies and linear deposits of immunoglobulin and complement along the glomerular basement membrane. When associated with pulmonary haemorrhage the condition is called goodpasture syndrome.
(12 Dec 1998)
glomerular <nephrology> Pertaining to or of the nature of a glomerulus, especially a renal glomerulus.
(14 Oct 1997)
glomerular capsule The expanded beginning of a nephron composed of an inner and outer layer: the visceral layer consists of podocytes which surround a tuft of capillaries (glomerulus); the parietal layer is simple squamous epithelium which becomes cuboidal at the tubular pole.
Synonym: capsula glomeruli, Bowman's capsule, malpighian capsule, Muller's capsule.
(05 Mar 2000)
glomerular crescent Proliferated epithelial cells partly encircling a renal glomerulus; it occurs in glomerulonephritis.
(05 Mar 2000)
glomerular cysts Cyst's formed by dilatation of Bowman's capsules, found in rare cases of congenital polycystic kidneys.
(05 Mar 2000)
glomerular layer of olfactory bulb A layer composed of spherical bodies, called glomeruli, formed by the synapses of mitral cells with the olfactory nerve fibres derived from the cells of the olfactory epithelium.
(05 Mar 2000)
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