| gigantism | A condition where there is over-production of growth hormone by the pituitary gland in a child before the bone growth plates close, resulting in excessive long bone growth. (27 Sep 1997) |
|---|
| acromegalic gigantism | A form of pituitary gigantism in which the signs of acromegaly accompany abnormal height. (05 Mar 2000) |
|---|---|
| cerebral gigantism | A syndrome characterised by increased birth weight and length (above 90th percentile), accelerated growth rate for the first 4 or 5 years without elevation of serum growth hormone levels, and then reversion to normal growth rate; characteristic facies include prognathism, hypertelorism, antimongoloid slant, and dolichocephalic skull; moderate mental retardation and impaired coordination are also associated. See: Sotos' syndrome. (05 Mar 2000) |
| pituitary gigantism | Excessive growth due to overactivity of the pituitary gland (specifically of the anterior pituitary). (12 Dec 1998) |
| primordial gigantism | Unusually large size from birth due to familial or genetic factors or intrauterine environment (e.g., maternal prediabetic state) and not to hyperpituitarism. (05 Mar 2000) |
| eunuchoid gigantism | Gigantism with deficient development of sexual organs; may be of pituitary or gonadal origin; gigantism accompanied by body proportions typical of hypogonadism during adolescence. (05 Mar 2000) |
| focal gigantism | <radiology> Neurofibromatosis, AVM, Klippel-Trenaunay-Weber syndrome, Beckwith-Wiedemann syndrome, Parks-Davis syndrome, haemangioma, JRA (12 Dec 1998) |
| foetal gigantism | Excessive foetal or newborn size, e.g., cerebral gigantism and infants of diabetic mothers. (05 Mar 2000) |