| ¿µ¹® | genetic engineering | ÇÑ±Û | À¯Àü°øÇÐ |
|---|---|---|---|
| ¼³¸í | 1. À¯ÀüÀÚÀÇ ÇÕ¼ºÀ̳ª º¯Çü µûÀ§¸¦ ¿¬±¸ÇÏ´Â Çй®. ÀÀ¿ë À¯ÀüÇÐÀÇ ÇÑ ºÐ¾ß·Î, º´ÀÇ Ä¡·á³ª ÀÌ·Î¿î »ê¹°ÀÇ ´ë·® »ý»êÀ» ¸ñÀûÀ¸·Î ÇÑ´Ù. 2. »ý¹°ÀÇ À¯ÀüÀÚ¸¦ ÀΰøÀûÀ¸·Î °¡°øÇÏ¿© Àΰ£¿¡°Ô ÇÊ¿äÇÑ ¹°ÁúÀ» ´ë·®À¸·Î °ª½Î°Ô ¾ò´Â ±â¼ú. 1970³â´ë¿¡ µé¾î¼¸é¼ °æÀÌÀûÀÎ °úÇбâ¼úÀÇ Çϳª·Î Å« ÁÖ¸ñÀ» ²ø°í ÀÖÀ¸¸ç, ÀÌ ºÐ¾ß¿¡´Â ÀçÁ¶ÇÕ DNA±â¼ú-¼¼Æ÷À¶ÇÕ±â¼ú ¹× ÇÙġȯ±â¼ú µîÀÌ ÀÖ´Ù. ÀçÁ¶ÇÕ DNA ±â¼ú¿¡ ÀÇÇÏ¿© ÀΰøÀûÀ¸·Î ÀçÁ¶ÇÕÀ¯ÀüÀÚ¸¦ ¸¸µç ÃÖÃÊÀÇ º¸°í´Â 1972³â Àè½¼ µîÀÌ ÇÏ¿´°í, ÀΰøÀû ÀçÁ¶ÇÕÀ¯ÀüÀÚ¸¦ ¼÷ÁÖ¼¼Æ÷¿¡¼ ÇüÁúÀ» ¹ßÇö½ÃŰ´Â µ¥ ÃÖÃÊ·Î ¼º°øÇÑ °ÍÀº 1973³â F. J. ÄÚº¥ µîÀÌ´Ù. ÀÌ ÀçÁ¶ÇÕ DNA ±â¼úÀº ¼¼±ÕÆÄÁö, Çö󽺹̵忡 °üÇÑ ¿¬±¸¿Í DNA¿¡ ÀÛ¿ëÇÏ´Â È¿¼Òµé, ƯÈ÷ Á¦ÇÑÈ¿¼Ò¿Í DNA ¿¬°áÈ¿¼Ò¿¡ °üÇÑ ¿¬±¸¿¡ ÀÇÁ¸ÇÏ¿´´Ù. À¯Àü°øÇÐÀÇ ¹ßÀüÀº ¿ì¸® ¼¼°è¸¦ ¹Ù²Ü ¼ö ÀÖÀ» °ÍÀ¸·Î ³»´Ùº¸°í ÀÖ´Ù. ¾ÏÀ» Á¦¾ÐÇÏ°í ³ëȸ¦ ¹æÁöÇÒ ¼ö ÀÖ¾î À¯Àü°øÇÐÀº °á±¹ ¿À´ÃÀÇ Àΰ£ÀÌ ¾È°í ÀÖ´Â ¿¡³ÊÁö-½Ä·®-ÀÇ·á µîÀÇ ¹®Á¦¸¦ ÇØ°áÇØ ÁÙ ¼ö ÀÖ´Â °¡´É¼ºÀ» Áö´Ñ´Ù. ÀÌ ¶§¹®¿¡ À¯Àü°øÇÐÀº ¡®Á¦3ÀÇ »ê¾÷Çõ¸í¡¯À̶ó°í ÇÒ ¼ö ÀÖ°í, µû¶ó¼ ±× °³¹ßÀ» À§ÇÏ¿© ¿Â ¼¼°èÀÇ ±â¾÷µéÀÌ ÀÌÀÇ ¿¬±¸°³¹ß¿¡ Âø¼öÇÏ°í ±¹°¡µéµµ Àü·«±â¼ú·Î ´Ù·ç¾î ÁýÁ¢ À°¼º¿¡ ¹ÚÂ÷¸¦ °¡Çϰí ÀÖ´Ù. ¿ì¸®³ª¶ó¿¡¼µµ 1982³âºÎÅÍ À¯Àü°øÇÐ ºÐ¾ß¸¦ ±¹°¡°¡ À°¼ºÇØ¾ß ÇÒ Æ¯Á¤¿¬±¸ ºÐ¾ß·Î ÁöÁ¤Çϰí ÀÖ´Ù. |
||
| ¿µ¹® | genetic code | ÇÑ±Û | À¯ÀüºÎÈ£ |
|---|---|---|---|
| ¼³¸í | ±æ°Ô ´Ã¾î¼ ÀÖ´Â DNA»ç½½ÀÇ À¯ÀüÁ¤º¸°¡ °¢°¢ÀÇ ¾Æ¹Ì³ë»ê¿¡ ´ëÀÀÇÏ¿© ´Ü¹éÁúÀÇ ÇÕ¼º¿¡ »ç¿ëµÉ ¼ö ÀÖ°Ô ÀÐÇôÁö´Â ¹æ¹ý. DNA ºÐÀÚ´Â °¢°¢ÀÇ Deoxyribonucleotide°¡ ¿¬°áµÇ¾î¼ ÀÌ·ç´Â ±¸Á¶ÀÌ´Ù. ÀÌDeoxyribonucleolide´Â ´ç, Àλê, ±×¸®°í ¿°±â·Î ÀÌ·ç¾îÁ® ÀÖ´Ù. ´ç°ú ÀλêÀº °¢°¢ÀÇ Deoxyribonucleotide°¡ ¿¬°áµÇ°Ô À¯ÁöÇØÁÖ´Â ¿ªÇÒÀ» ÇÏ°í ¿°±â°¡ À¯ÀüÁ¤º¸¸¦ °¡Áö°í ÀÖÀ¸¸ç ÀÌ ¿°±âÀÇ ¹è¿ÀÌ À¯ÀüÁ¤º¸ Áï ´Ü¹éÁúÀÇ ÇÕ¼º¿¡ ÇÊ¿äÇÑ Á¤º¸¸¦ °¡Áö°í ÀÖ´Ù. DNA¸¦ ÀÌ·ç´Â ¿°±â´Â 4°³·Î ¾Æµ¥´Ñ(adenine), ±¸¾Æ´Ñ(guanine), Ƽ¹Î(thymine), ½ÃÅä½Å(cytosine)ÀÇ 4°¡ÁöÀÌ´Ù. 4°³ÀÇ ¿°±â°¡ ¼¯¿©ÀÖ´Â ¹è¿À» ÇÑ °³ÀÇ ´Ü¹éÁú·Î ÇÕ¼ºÀ» Çϱâ À§Çؼ´Â ÀÌ ¹è¿À» ÇØµ¶ÇÏ´Â ¹æ¹ýÀÌ ÀÖ¾î¾ß ÇÑ´Ù. Áï ±× ¹æ¹ýÀº 3°³ÀÇ ¿°±âÀÇ ¹è¿À» ÇϳªÀÇ ¾Æ¹Ì³ë»ê¿¡ ´ëÀÀ½ÃÄѼ °¢ ¾Æ¹Ì³ë»êÀÇ ¼¿À» Á¤ÇÏ°í ´Ü¹éÁúÀ» ¸¸µå´Â °ÍÀÌ´Ù. ¿¹¸¦ µé¸é cytosine-cytosine-cytosineÀ̶ó´Â ¹è¿Àº prolineÀ̶ó´Â ´Ü¹éÁúÀ» ÀǹÌÇÏ´Â °ÍÀ¸·Î ÀÐÇôÁö°Ô µÈ´Ù. ÀÌ·¸°Ô ¾Æ¹«·± ±ÔÄ¢ÀÌ ¾ø´Â °Í °°Àº ¿°±â¼¿À» ÇϳªÀÇ ¾Æ¹Ì³ë»ê°ú ´ëÀÀ½ÃÄѼ Àд ¹æ¹ýÀÌ À¯ÀüºÎÈ£ÀÌ´Ù. |
||
| CNV | choroidal neovascularization; contingent negative variation; cutaneous necrotizing vasculitis |
|---|---|
| CV | cardiac volume; cardiovascular; carotenoid vesicle; cell volume; central venous; cephalic vein; cere... |
| NV | nausea and vomiting; negative variation; neovascularization; next visit; nonveteran; normal value; n... |
| PINV | postimperative negative variation |
| TCNV | terminal contingent negative variation |
| GAERS | Genetic Absence Epilepsy Rat from Strasbourg |
|---|---|
| GA | Genetic Algorithm |
| GH | Genetic Hemochromatosis |
| GSE | genetic suppressor element |
| PGD | Pre-implantation Genetic Diagnosis |
| antigenic variation | The phenomenon of changes in surface antigens in parasitic populations of Trypanosoma and Plasmodium (and some other parasitic protozoa) in order to escape immunological defense mechanisms. at least 100 different surface proteins have been found to appear and disappear during antigenic variation in a clone of trypanosomes. Each antigen is encoded in a separate gene. Antigenic variation is also known to occur in free living Protozoa and certain bacteria. (18 Nov 1997) |
|---|---|
| variation | In genetics, deviation in characters in an individual from those typical of the group to which it belongs, also, deviation in characters of the offspring from those of its parents. (18 Nov 1997) |
| variation (genetics) | The phenotypic differences among individuals in a population. (12 Dec 1998) |
| phase variation | <microbiology> Alteration in the expression of surface antigens by bacteria. For example: Salmonella can express either of two forms of flagellin, H1 and H2, that are coded by different genes. Control of which form is expressed is brought about by inversion of the promoter for the H2 gene, which if functional (noninverted) is associated with the expression of H2 and the production of a repressor of the H1 gene. Inversion occurs about every 1000 bacterial divisions and is under the control of another gene, hin, that is within the invertable sequence. (31 Dec 1997) |
| coefficient of variation | The ratio of the standard deviation to the mean. (05 Mar 2000) |
| contingent negative variation | An increasing negative shift of the cortical electrical potentials associated with an anticipated response to an expected stimulus. It is an electrical event indicative of a state of readiness or expectancy. (12 Dec 1998) |
| somaclonal variation | The variation between individuals in a clone, particularly in plant clones. While the objective is usually to grow clones without variation, somaclonal variation does provide the opportunity to generate new plant types that would be harder or impossible to generate by conventional plant breeding. (14 Nov 1997) |
| isotypic variation | <immunology> Variability of antigens common to all members of a species, for example the five classes of immunoglobulins found in humans. See: idiotype and allotype. (18 Nov 1997) |
| observer variation | The failure by the observer to measure or identify a phenomenon accurately, which results in an error. Sources for this may be due to the observer's missing an abnormality, or to faulty technique resulting in incorrect test measurement, or to misinterpretation of the data. Two varieties are inter-observer variation (the amount observers vary from one another when reporting on the same material) and intra-observer variation (the amount one observer varies between observations when reporting more than once on the same material). (12 Dec 1998) |
| genetic | <biology> Pertaining to reproduction or to birth or origin. (07 May 1998) |
| genetic amplification | A process for producing an increase in pertinent genetic material, particularly for increasing the proportion of plasmid DNA to that of bacterial DNA. Includes the production of extrachromosomal copies of the genes for RNA. (05 Mar 2000) |
| genetic assimilation | <genetics> A situation in which a characteristic that is normally expressed only in certain environmental situations becomes fixed in a population so that it no longer requires environmental factors to be expressed. (07 May 1998) |
| genetic association | The occurrence together in a population, more often than can be readily explained by chance, of two or more traits of which at least one is known to be genetic. (05 Mar 2000) |
| genetic block | <biochemistry, molecular biology> An obstruction in a biochemical pathway caused by a mutation that has crippled production of an enzyme critical to the pathway. (07 May 1998) |
| genetic burden | The genetic debt due to harmful mutation but as yet undischarged. (In a large population of fixed size every mutation with diminished genetic fitness will eventually become extinct and depending on the details of inheritance and phenotype must be paid for by a fixed number of genetic deaths per mutation, the genetic debt.) (05 Mar 2000) |
Á¦Ç°¸í |
ÆÇ¸Å»ç |
º¸ÇèÄÚµå | ¼ººÐ/ÇÔ·® | ±¸ºÐ/º¸Çè±Þ¿© |
|---|
Á¦Ç°¸í |
ÆÇ¸Å»ç |
º¸ÇèÄÚµå | ¼ººÐ/ÇÔ·® | ±¸ºÐ/º¸Çè±Þ¿© |
|---|