genes, erbb : KMLE 의학 검색 엔진 - 의학사전, 의학용어, 의학약어, 의학논문, 약품/의약품 검색

MeSH(Medical Subject Headings) 맞춤 검색 (http://www.nlm.nih.gov) 결과 : 3 페이지: 1

Genes, erbB - 새창 Retrovirus-associated DNA sequences (erbB) originally isolated from, or related to, the avian erythroblastosis virus (AEV). These genes code for the epidermal growth factor receptor (EGFR) family of receptors which is important in the control of normal cell proliferation and in the pathogenesis of human cancer. The genes include erbB-1 (GENES, ERBB-1), erbB-2 (GENES, ERBB-2), and erbB-3, all of which show abnormalities of expression in various human neoplasms.
Synonyms : Genes, c-erbB-3, c erbB 3 Genes, c-erbB-3 Gene, erbB 3 Genes, erbB Gene, erbB-3 Gene
Genes, erbB-1 - 새창 The proto-oncogene c-erbB-1 codes for the epidermal growth factor receptor. Its name originates from the viral homolog v-erbB which was isolated from an avian erythroblastosis virus (AEV) where it was contained as a fragment of the chicken c-ErbB-1 gene lacking the amino-terminal ligand-binding domain. Overexpression of erbB-1 genes occurs in a wide range of tumors, commonly squamous carcinomas of various sites and less commonly adenocarcinomas. The human c-erbB-1 gene is located in the chromosomal region 7p14 and 7p12.
Synonyms : Genes, erbB1, c-erbB-1 Proto-Oncogenes, v-erbB Oncogenes, EGFR Gene, Gene, erbB1, c erbB 1 Genes, c erbB 1 Proto Oncogenes, c-erbB-1 Gene, c-erbB-1 Proto-Oncogene, erbB 1 Genes, erbB-1 Gene, erbB1 Gene, erbB1 Genes, v erbB Genes, v erbB Oncogenes, v-erbB Gene
Genes, erbB-2 - 새창 The erbB-2 gene is a proto-oncogene that codes for the erbB-2 receptor (RECEPTOR, ERBB-2), a protein with structural features similar to the epidermal growth factor receptor. Its name originates from the viral oncogene homolog (v-erbB) which is a truncated form of the chicken erbB gene found in the avian erythroblastosis virus. Overexpression and amplification of the gene is associated with a significant number of adenocarcinomas. The human c-erbB-2 gene is located at 17q21.2.
Synonyms : Genes, HER2, Genes, erbb2, c-erbB-2 Proto-Oncogenes, Gene, HER2, Gene, erbb2, HER-2 Gene, HER-2 Genes, HER2 Gene, HER2 Genes, c erbB 2 Genes, c erbB 2 Proto Oncogenes, c-erbB-2 Gene, c-erbB-2 Proto-Oncogene, erbB 2 Genes, erbB-2 Gene, erbb2 Gene, erbb2 Genes, neu Gene