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| SSP | Sanarelli-Shwartzman phenomenon; subacute sclerosing panencephalitis; slice sensitivity profile; sub... |
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| GSR | galvanic skin response; generalized Shwartzman reaction; glutathione reductase |
| GSSR | generalized Sanarelli-Shwartzman reaction |
| SGR | Sachs-Georgi reaction; Shwartzman generalized reaction; skin galvanic reflex; submandibular gland re... |
| SLR | Shwartzman local reaction; single lens reflex; straight leg raising |
| GSR | Generalized Shwartzman reaction |
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| PRP | Primary Raynaud's Phenomenon |
| RP | Raynaud Phenomenon |
| GAM | Generalised Additive Models |
| GAD | Generalised Anxiety Disorder |
| generalised Shwartzman phenomenon | When both the primary injection of endotoxin-containing filtrate and the secondary injection are given intravenously 24 hours apart, the animal usually dies within 24 hours after the second inoculation; the characteristic lesions in the rabbit include widespread haemorrhages in the lung, liver, and other organs and bilateral cortical necrosis of the kidney. This reaction has no immunological basis. Synonym: Sanarelli phenomenon, Sanarelli-Shwartzman phenomenon. (05 Mar 2000) |
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| Sanarelli-Shwartzman phenomenon | When both the primary injection of endotoxin-containing filtrate and the secondary injection are given intravenously 24 hours apart, the animal usually dies within 24 hours after the second inoculation; the characteristic lesions in the rabbit include widespread haemorrhages in the lung, liver, and other organs and bilateral cortical necrosis of the kidney. This reaction has no immunological basis. Synonym: Sanarelli phenomenon, Sanarelli-Shwartzman phenomenon. (05 Mar 2000) |
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| shwartzman phenomenon | A two-stage reaction in which a first encounter with endotoxin produces intravascular fibrin thrombi whose clearance results in reticuloendothelial blockade which prevents the clearance of thrombi caused by a second encounter with endotoxin, resulting in tissue necrosis and/or haemorrhage. In pregnancy gram-negative septicaemia during delivery or abortion may serve as the first or provocative encounter. The phenomenon is non-immunologic and is known to occur only in rabbits and man. (12 Dec 1998) |
| Shwartzman, Gregory | <person> Russian bacteriologist in U.S., 1896-1965. See: Shwartzman phenomenon, Shwartzman reaction, generalised Shwartzman phenomenon, Sanarelli-Shwartzman phenomenon. (05 Mar 2000) |
| Shwartzman reaction | <investigation> Reaction that occurs when two injections of endotoxin are given to the same animal, particularly rabbits, 24h apart. In the local Shwartzman reaction the first injection is given intradermally, the second intravenously and a haemorrhagic reaction develops at the dermal site. If both injections are intravenous the result is a generalised Shwartzman reaction, often accompanied by disseminated intravascular coagulation. The reaction depends upon the response of platelets and neutrophils to endotoxin. (18 Nov 1997) |
| generalised | <zoology> Comprising structural characters which are separated in more specialized forms; synthetic; as, a generalised type. Source: Websters Dictionary (01 Mar 1998) |
| generalised anaphylaxis | The immediate response, involving smooth muscles and capillaries throughout the body of a sensitised individual, that follows intravenous (and occasionally intracutaneous) injection of antigen (allergen). See: anaphylactic shock. Synonym: systemic anaphylaxis. (05 Mar 2000) |
| generalised anxiety disorder | Chronic, repeated episodes of anxiety reactions; a psychological disorder in which anxiety or morbid fear and dread accompanied by autonomic changes are prominent features. See: anxiety. (05 Mar 2000) |
| generalised chondromalacia | A degenerative disease of cartilage producing a bizarre form of arthritis, with collapse of the ears, the cartilaginous portion of the nose, and the tracheobronchial tree; death may occur from chronic infection or suffocation because of loss of stability in the tracheobronchial tree of autosomal origin. Synonym: chronic atrophic polychondritis, generalised chondromalacia, Meyenburg's disease, Meyenburg-Altherr-Uehlinger syndrome, relapsing perichondritis, systemic chondromalacia, von Meyenburg's disease. (05 Mar 2000) |
| generalised cortical hyperostosis | <syndrome> An inherited skeletal dysplasia, with mandibular enlargement and thickening of the diaphyses and calvaria, and increased serum alkaline phosphatase; autosomal recessive inheritance. Synonym: generalised cortical hyperostosis. (05 Mar 2000) |
| generalised elastolysis | A group of connective tissue diseases in which skin hangs in loose pendulous folds. It is believed to be associated with decreased elastic tissue formation as well as an abnormality in elastin formation. Cutis laxa is usually a genetic disease, but acquired cases have been reported. (12 Dec 1998) |
| generalised emphysema | Emphysema affecting all parts of the lobules, in part, or usually the whole, of the lungs, and usually associated with a1-antiprotease deficiency emphysema. Synonym: diffuse emphysema, generalised emphysema, panacinar emphysema. (05 Mar 2000) |
| generalised epidermolytic hyperkeratosis | Diffusely red, eroded skin at birth, with subsequent scaling, tending to improve in later life, characterised by generalised epidermolytic hyperkeratosis and autosomal dominant inheritance. See: epidermolytic hyperkeratosis. Synonym: generalised epidermolytic hyperkeratosis, ichthyismus hystrix, ichthyosis hystrix. (05 Mar 2000) |
| generalised epilepsy | A major category of epilepsy syndromes characterised by one or more types of generalised seizures. (05 Mar 2000) |
| generalised eruptive histiocytoma | A rare recurring generalised eruption in adults of flesh coloured or erythematous papules remaining localised to the skin and consisting of dermal nodules of mononuclear histiocytes that do not stain for lipid. Synonym: nodular non-X histiocytosis. (05 Mar 2000) |
| generalised gangliosidosis | Three forms exist: infantile, generalised; juvenile; and adult; gangliosidosis characterised by accumulation of a specific monosialoganglioside, GM1; due to deficiency of GM1-beta-galactosidase. Synonym: generalised gangliosidosis. (05 Mar 2000) |
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