| 영문 | gene | 한글 | 유전자 |
|---|---|---|---|
| 설명 | 유전자는 길게 띠를 형성한 DNA분자의 일부분으로 한 가지 물질을 만드는데 필요한 모든 정보를 갖춘 기능적인 단위이다. 예를 들어 인슐린이라는 물질의 유전자라고 하면 사람의 세포내에 있는 긴 DNA 분자 중에서 인슐린이라는 물질을 만드는데 필요한 모든 정보를 가지고 있는 한 부분을 가리키는 말이다. 고전적인 생물학에서는 유전자가 표현형을 결정하거나 지정하는 염색체의 일부분이라고 정의되었지만, 오늘날에는 유전자에 대해서 분자적 정의가 제안되고 있으며 그 정의는 하나의 유전자는 하나의 효소를 결정 또는 암호화하는 유전물질의 일부분이라는 개념으로 이것이 이른바 1개의 유전자 1개 효소가설(one gene-one enzyme hypothesis)이다. 즉 1개의 유전자는 1개의 효소를 제작하는데 필요한 유전정보를 가진다는 것이다. 현재 이 가설이 받아들여지고 있다. |
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| 영문 | gene therapy | 한글 | 유전자요법 |
|---|---|---|---|
| 설명 | 유전병을 치료할 목적으로, 정상적으로 기능하는 단일유전자 혹은 복수유전자를 어떤 기원에서 얻어내어 생세포에 도입하는 것. 유전물질은 유전자삽입 조작에 의해 수용세포에로 도입된다. 즉, 유전자를 끼워 넣은 새로운 세포를 사용하는 치료로서 1980년 미국의 학자가 지중해빈혈환자에게 강행하여 비판을 받았지만, 미국 국립보건연구소는 1990년 9월 아데노신 데아미나아제(adenosine deaminase, ADA) 결핍증 환자의 림프구에 ADA 유전자를 끼워 넣는 치료를 시작한 이래 현재는 암을 포함한 많은 질병들을 치료하는 목적으로 쓰인다. |
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| dpdt | double-pole double-throw [switch] |
|---|---|
| dpst | double-pole single-throw [switch] |
| SCS | Saethre-Chotzen syndrome; shared computer system; silicon-controlled switch; Society of Clinical Sur... |
| CGRP | Calcitonin Gene Related Peptide(Protein) |
| CGRPs | Calcitonin Gene-Related Products |
| ASO | Arterial switch operation |
|---|---|
| CSR | class switch recombination |
| S | switch |
| 16S rDNA | 16S rRNA gene |
| PGK | 3-phosphoglycerate kinase gene |
| gene switch | <molecular biology> A situation in which a cell or organism stops expressing one gene orgene group and switches to expressing a different gene or group of genes. (09 Oct 1997) |
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| arterial switch operation | Operation for complete transposition of the great arteries; the most common way to repair this defect consists of switching the aorta and pulmonary arteries and implanting the coronary arteries into the neoaorta (the original pulmonary artery). (05 Mar 2000) |
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| genes, switch | Genes that cause the epigenotype (i.e., the interrelated developmental pathways through which the adult organism is realised) to switch to an alternate cell lineage-related pathway. Switch complexes control the expression of normal functional development as well as oncogenic transformation. (12 Dec 1998) |
| class switch | Change in the isotype of antibody produced after a B-cell has encountered an antigen. (05 Mar 2000) |
| switch | 1. To strike with a switch or small flexible rod; to whip. 2. To swing or whisk; as, to switch a cane. 3. To trim, as, a hedge. 4. To turn from one railway track to another; to transfer by a switch; generally with off, from, etc.; as, to switch off a train; to switch a car from one track to another. 5. To shift to another circuit. Origin: Switched; Switching. 1. A small, flexible twig or rod. "Mauritania, on the fifth medal, leads a horse with something like a thread; in her other hand she holds a switch." (Addison) 2. A movable part of a rail; or of opposite rails, for transferring cars from one track to another. 3. A separate mass or trees of hair, or of some substance (at jute) made to resemble hair, worn on the head by women. 4. A mechanical device for shifting an electric current to another circuit. Safety switch, an arrangement of tracks whereby elevations otherwise insurmountable are passed. The track ascends by a series of zigzags, the engine running alternately forward and back, until the summit is reached. <physics> Switch board, a collection of switches in one piece of apparatus, so arranged that a number of circuits may be connected or combined in any desired manner. Switch grass. <botany> See Grass. Origin: Cf. OD. Swick a scourage, a whip. Cf. Swink, Swing. Source: Websters Dictionary (01 Mar 1998) |
| switch region | <molecular biology> The nucleotide sequences in heavy chain immunoglobulin genes located in the introns at the 5' end of each CH locus concerned with DNA recombination events that lead to changes in the type of heavy chain produced by a B-cell, for example IgM to IgG switching. These regions are highly conserved sequences. See: isotype switching. (19 Jan 1998) |
| immunoglobulin switch region | Site on a segment of a B-cell immunoglobulin heavy-chain gene where recombination or rearrangement can occur, expressed as isotype or allotype switching, maturation of immune response, or recombination of DNA molecules. It is found on genes encoding all five immunoglobulin heavy chains. (12 Dec 1998) |
| q-switch | <radiobiology> Optical switch used to rapidly change the Q of an optical resonator, utilised in the optical resonator of a laser to prevent lasing action until a high level of gain and energy storage are achieved in the laser medium. When the switch is triggered and rapidly increases the Q of the cavity, a stronger laser pulse is generated. See: oscillator. (09 Oct 1997) |
| allelic gene | See: allele, dominance of traits. (05 Mar 2000) |
| antibiotic resistance gene | Genes in a microorganism which confer resistance to antibiotics, for example by coding for enzymes which destroy it, by coding for surface proteins which prevent it from entering the microorganism, or by being a mutant form of the antibiotic's target so that it can ignore it. (09 Oct 1997) |
| autosomal gene | A gene located on any chromosome other than the sex chromosomes (X or Y). (05 Mar 2000) |
| bicoid gene | A group of genes which are important to the proper development of the head and thorax in the embryo of the fruit fly Drosophila melanogaster. (09 Oct 1997) |
| BRCA1 breast cancer susceptibility gene | This mutated (changed) version of the BRCA1 gene makes a person susceptible to developing breast cancer. (12 Dec 1998) |
| calcitonin gene-related peptide | <protein> A second product transcribed from the calcitonin gene. Calcitonin gene related peptide is found in a number of tissues including nervous tissue. It is a vasodilator that may participate in the cutaneous triple response. It is a neuropeptide of 37 amino acids with structural homology to salmon calcitonin. Co-localises with substance P in neurons. It occurs as a result of alternative processing of mRNA from the calcitonin gene. The neuropeptide is widely distributed in neural tissue of the brain, gut, perivascular nerves, and other tissue. The peptide produces multiple biological effects and has both circulatory and neurotransmitter modes of action. In particular, it is a potent endogenous vasodilator. Intracerebral administration leads to a rise in noradrenergic sympathetic outflow, a rise in blood pressure and a fall in gastric secretion. Acronym: CGRP (05 May 2002) |
| cancer susceptibility gene | tumour suppressor gene |
| rab gene | 1. <molecular biology> One of the three main groups of ras like genes specifying small GTP-binding proteins (the others are ras and rho). Rab proteins are involved in vesicular traffic and seem to control translocation from donor to acceptor membranes. 2. <cell biology> Gene family in plants responsive to abscisic acid: encode proteins of 15-17 kD. (18 Nov 1997) |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|