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gap j. a type of intercellular junction comprising a narrowed portion (about 3 nm) of the intercellular space that contains channels or pores (about 2 nm) composed of hexagonal arrays of membrane-spanning proteins around a central lumen (connexon) through which pass ions and small molecules such as most sugars, amino acids, nucleotides, vitamins, hormones, and cyclic AMP. In electrically excitable tissues, these gap junctions serve to transmit electrical impulses via ionic currents and are known as electrotonic synapses; they are present in such tissues as myocardial tissue and the central nervous system. Called also nexus. Click here to view image■Gap junctions providing passageways between the interiors of adjacent cells.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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