| 영문 | gene | 한글 | 유전자 |
|---|---|---|---|
| 설명 | 유전자는 길게 띠를 형성한 DNA분자의 일부분으로 한 가지 물질을 만드는데 필요한 모든 정보를 갖춘 기능적인 단위이다. 예를 들어 인슐린이라는 물질의 유전자라고 하면 사람의 세포내에 있는 긴 DNA 분자 중에서 인슐린이라는 물질을 만드는데 필요한 모든 정보를 가지고 있는 한 부분을 가리키는 말이다. 고전적인 생물학에서는 유전자가 표현형을 결정하거나 지정하는 염색체의 일부분이라고 정의되었지만, 오늘날에는 유전자에 대해서 분자적 정의가 제안되고 있으며 그 정의는 하나의 유전자는 하나의 효소를 결정 또는 암호화하는 유전물질의 일부분이라는 개념으로 이것이 이른바 1개의 유전자 1개 효소가설(one gene-one enzyme hypothesis)이다. 즉 1개의 유전자는 1개의 효소를 제작하는데 필요한 유전정보를 가진다는 것이다. 현재 이 가설이 받아들여지고 있다. |
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| 영문 | gene therapy | 한글 | 유전자요법 |
|---|---|---|---|
| 설명 | 유전병을 치료할 목적으로, 정상적으로 기능하는 단일유전자 혹은 복수유전자를 어떤 기원에서 얻어내어 생세포에 도입하는 것. 유전물질은 유전자삽입 조작에 의해 수용세포에로 도입된다. 즉, 유전자를 끼워 넣은 새로운 세포를 사용하는 치료로서 1980년 미국의 학자가 지중해빈혈환자에게 강행하여 비판을 받았지만, 미국 국립보건연구소는 1990년 9월 아데노신 데아미나아제(adenosine deaminase, ADA) 결핍증 환자의 림프구에 ADA 유전자를 끼워 넣는 치료를 시작한 이래 현재는 암을 포함한 많은 질병들을 치료하는 목적으로 쓰인다. |
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| AG | 1) Amino-Glycoside 2) Anion Gap - Anion Gap |
|---|---|
| GAP | Group for Advancement of Psychiatry |
| GAP syndrome | Galactorrhea, Amenorrhea, Prolactinoma Syndrome |
| OG | Osmolar Gap; 10 mOsm/kg = measured Osm - calculated Osm |
| AG | abdominal girth; agarose; aminoglutethimide; analytical grade; anion gap; antigen; antiglobulin; ant... |
| AG | Anion gap |
|---|---|
| GAP | D-glyceraldehyde 3-phosphate |
| GRD | GAP related domain |
| GAP | GTP-ase-activating protein |
| GJIC | Gap Junctional Intercellular Communication |
| gap gene | <molecular biology> Segmentation genes involved in specifying relatively coarse subdivisions of the embryo. They are expressed sequentially in development between egg polarity genes and pair rule genes. In Drosophila, there are at least three such genes, for example Kruppel. (18 Nov 1997) |
|---|
| air-bone gap | The difference between the threshold for hearing acuity by bone conduction and by air conduction. (05 Mar 2000) |
|---|---|
| air-gap radiography | Chest radiography with a space (at least 10 inches) between the subject and film. Instead of using a grid, this method uses the geometry and X-ray absorption by the air to remove scattered radiation. (05 Mar 2000) |
| air-gap technique | Chest radiography performed using a space between the subject and film instead of a grid to absorb scattered radiation; usually requires a target-film distance of 10 feet. (05 Mar 2000) |
| anion gap | <biochemistry> The difference between the sum of the measured cations and anions in the plasma or serum calculated as follows: (Na + K) -(Cl + HCO3) = < 20 mmol/l. Elevated values may occur in diabetic or lactic acidosis; normal or low values occur in bicarbonate-losing metabolic acidoses. Synonym: cation-anion difference. (05 Mar 2000) |
| auscultatory gap | The period during which Korotkoff sounds indicating true systolic pressure fade away and reappear at a lower pressure point; responsible for errors made in recording falsely low systolic blood pressure, especially in hypertensive patients, of up to 25 mm Hg, and avoided by pumping the cuff 30 mm Hg beyond palpable systolic pressure. Synonym: silent gap. (05 Mar 2000) |
| Bochdalek's gap | A triangular area in the diaphragm near the lateral arcuate ligament that is devoid of muscle fibres; it is covered by pleura superiorly and by peritoneum inferiorly. Synonym: Bochdalek's gap, trigonum lumbocostale. (05 Mar 2000) |
| gap | A space in between two of the same objects, where part of a chain or object is missing, or where certain activities, processes, or events are lacking. A period of time characterised by a lack of activity, in between two events or within a continuous process. <genetics, molecular biology> A gap is a spot on a strand of DNA or RNA where a nucleotide or a segment of nucleotides is missing. (09 Oct 1997) |
| gap 1 | In the somatic cell cycle, the gap that follows mitosis and is followed by synthesis in preparation for the next cycle. (05 Mar 2000) |
| GAP-1 receptor tyrosine kinase | <enzyme> Similar to rasGTPase-activating proteins; inhibits signaling activity of let-60; amino acid sequence given in first source Registry number: EC 2.7.1.- Synonym: gap-1 gene product, gap-1 protein (26 Jun 1999) |
| gap 2 | In the somatic cell cycle, a pause between completion of synthesis and the onset of cell division. (05 Mar 2000) |
| gap-43 protein | A nervous tissue specific protein which is highly expressed in neurons during development and nerve regeneration. It has been implicated in neurite outgrowth, long-term potentiation, signal transduction, and neurotransmitter release. It is also a substrate of protein kinase c. (12 Dec 1998) |
| gap arthroplasty | The surgical correction of ankylosis by creating a space between the ankylosed part of a joint and the portion for which movement is desired. (05 Mar 2000) |
| gap junction | <cell biology> A junction between two cells consisting of many pores that allow the passage of molecules up to about 900D. Each pore is formed by an hexagonal array (connexon) of six transmembrane proteins (connexins) in each plasma membrane: when mated together the pores open, allowing communication and the interchange of metabolites between cells. Electrical synapses are gap junctions and metabolic cooperation depends upon the formation of gap junctions. (18 Nov 1997) |
| gap junctions | Connections between cells which allow passage of small molecules and electric current. Gap junctions were first described anatomically as regions of close apposition between cells with a narrow (1-2 nm) gap between cell membranes. The variety in the properties of gap junctions is reflected in the number of connexins, the family of proteins which form the junctions. (12 Dec 1998) |
| gap mutant | <molecular biology> A fruit fly of the genus Drosophila which is missing a number of adjacent segments because the segments failed to develop. (09 Oct 1997) |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|