| catabolite gene activator protein | <molecular biology, protein> A regulatory protein that triggers the transcription of genes that generate the enzymes bacteria need to usenutrients when glucose isabsent. (16 Mar 1998) |
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| catabolite (gene) activator protein | A protein that can be activated by cAMP, whereupon it affects the action of RNA polymerase by binding it with it or near it on the DNA to be transcribed. Synonym: cAMP receptor protein, catabolite gene activator. (05 Mar 2000) |
| protein activator, aminolevulinic acid synthetase | <chemical> From rat liver mitochondria Synonym: aminolevulinic acid synthetase activator (26 Jun 1999) |
| ganglioside | <biochemistry> A glycosphingolipid that contains one or more residues of N acetyl or other neuraminic acid derivatives. Gangliosides are found in highest concentration in cells of the nervous system, where they can constitute as much as 5% of the lipid. (18 Nov 1997) |
| ganglioside galactosyltransferase | <enzyme> Consider also EC 2.4.1.45 Registry number: EC 2.4.1.62 Synonym: udpgalactose-n-acetylgalactosaminyl-(n-acetylneuraminyl)-galactosyl-glucosyl-ceramide galactosyltransferase, udpgalactose-gm2 galactosyltransferase, ganglioside gm1 synthase, udpgalactose-ceramide galactosyltransferase, udp-galactose-gm2 gangliosidebeta-1-3-galactosyltransferase, udpgal-gm2 beta1-3-galactosyltransferase (26 Jun 1999) |
| ganglioside lipidosis | Any disease characterised, in part, by the abnormal accumulation within the nervous system of specific gangliosides, e.g., GM2 gangliosidosis, Tay-Sachs disease, caused by hexosaminidase A enzyme deficiency with accumulation of GM2 ganglioside Synonym: gangliosialidosis, ganglioside lipidosis. (05 Mar 2000) |
| ganglioside O-acetyltransferase | <enzyme> Gd2 ganglioside is an acceptor for the above enzyme in human melanoma cells Registry number: EC 2.3.1.- (26 Jun 1999) |
| g(m1) ganglioside | <chemical> Galactosyl-n-acetylgalactosaminyl-(n-acetylneuraminyl)- galactosyl-glucosylceramide. Ganglioside present in abnormally large amounts in neurons and in elevated levels in liver and kidney due to a deficiency of beta-galactosidase in the genetically determined disease gm1-gangliosidosis. Chemical name: Ganglioside GM1 (12 Dec 1998) |
| g(m2) ganglioside | <chemical> N-acetylgalactosaminyl-galactosyl-(n-acetylneuraminyl)-glucosyl-ceramide. This is the defective ganglioside manifested in tay-sachs disease and sandhoff disease. Chemical name: Ganglioside GM2 (12 Dec 1998) |
| g(m3) ganglioside | N-acetylneuraminyl-galactosyl-glucosylceramide. This ganglioside is present in abnormally large amounts in the brain and liver due to a deficient biosynthetic enzyme, g(m3):udp-n-acetylgalactosaminyltransferase. Deficiency of this enzyme prevents the formation of g(m2) ganglioside from g(m3) ganglioside and is the cause of an anabolic sphingolipidosis. (12 Dec 1998) |
| GM3 ganglioside sialidase | <enzyme> Enzyme deficient in mucolipidosis iv Registry number: EC 3.2.1.- Synonym: haematoside neuraminidase, ganglioside sialidase (26 Jun 1999) |
| activator | <biochemistry> A DNA-binding transcription metabolite that positively modulates an allosteric enzyme or regulates one or more genes by increasing the rate of transcription. (12 Mar 1998) |
| activator appliances | Loose-fitting removable orthodontic appliances which redirect the pressures of the facial and masticatory muscles onto the teeth and their supporting structures to produce improvements in tooth arrangements and occlusal relations. (12 Dec 1998) |
| catabolite gene activator | catabolite (gene) activator protein |
| plasminogen activator | <enzyme> Serine protease that acts on plasminogen to generate plasmin. Has also been implicated in invasiveness and is produced by many normal and invasive cells. The vascular form (tPA, 55 kD) is very similar to tissue plasminogen activator (uPA, 70 kD) and to streptokinase and urokinase. (18 Nov 1997) |