| GABA, gaba | gamma-aminobutyric acid |
|---|---|
| GABA | Gamma-Amino-Butyric Acid |
| GABAT, GABA-T | gamma-aminobutyric acid transaminase |
| GABA-T | GABA aminotransferase |
|---|---|
| GABA-IR | GABA immunoreactive |
| GABA(A)-R | GABA(A) receptor |
| GABA-T | GABA transaminase |
| GABA(A) | GABA type A |
| gaba agonists | Drugs that bind to and activate gaba receptors (receptors, gaba). (12 Dec 1998) |
|---|
| adrenergic agonists | Drugs that bind to and activate adrenergic receptors. (12 Dec 1998) |
|---|---|
| adrenergic alpha-agonists | Drugs that selectively bind to and activate alpha adrenergic receptors. (12 Dec 1998) |
| adrenergic beta-agonists | Drugs that selectively bind to and activate beta-adrenergic receptors. (12 Dec 1998) |
| cholinergic agonists | Drugs that bind to and activate cholinergic receptors. (12 Dec 1998) |
| myeloablative agonists | Agents that destroy bone marrow activity. They are used to prepare patients for bone marrow or stem cell transplantation. (12 Dec 1998) |
| serotonin agonists | Agents that have an affinity for serotonin receptors and are able to mimic the effects of serotonin by stimulating the physiologic activity at the cell receptors. These compounds are used as antidepressants, anxiolytics, and in the treatment of migraine. (12 Dec 1998) |
| nicotinic agonists | Drugs that bind to and activate nicotinic cholinergic receptors (receptors, nicotinic). Nicotinic agonists act at postganglionic nicotinic receptors, at neuroeffector junctions in the peripheral nervous system, and at nicotinic receptors in the central nervous system. Agents that function as neuromuscular depolarising blocking agents are included here because they activate nicotinic receptors, although they are used clinically to block nicotinic transmission. (12 Dec 1998) |
| dopamine agonists | Drugs that bind to and activate dopamine receptors. (12 Dec 1998) |
| excitatory amino acid agonists | Drugs that bind to and activate excitatory amino acid receptors. (12 Dec 1998) |
| lhrh agonists | Compounds that are similar to LHRH (luteinizing hormone-releasing hormone). (12 Dec 1998) |
| GABA | <biochemistry> An important amino acid which functions as the most prevalent inhibitory neurotransmitter in the central nervous system. Gamma aminobutyric acid works in partnership with a derivative of Vitamin B-6, pyridoxine, to cross from the axons to the dendrites through the synaptic cleft, in response to an electrical signal in the neuron and inhibits message transmission. This helps control the nerve cells from firing too fast, which would overload the system. The action of gamma aminobutyric acid decreases epileptic seizures and muscle spasms by inhibiting electrical signals in this manner. Studies have shown that the site of action in the brain of benzodiazepams, including Valium, is directly coupled to the brain receptor for gamma aminobutyric acid. Acronym: GABA (05 Jan 1998) |
| gaba agents | Substances used for their pharmacological actions on gabaergic systems. Gabaergic agents include agonists, antagonists, degradation or uptake inhibitors, depleters, precursors, and modulators of receptor function. (12 Dec 1998) |
| gaba antagonists | Drugs that bind to but do not activate gaba receptors, thereby blocking the actions of endogenous gaba or gaba agonists. (12 Dec 1998) |
| GABA dehydrogenase | <enzyme> From crude mitochondrial fraction of rat brain; reported first product is gamma-aminocrotonic acid; p-iodonitrotetrazolium violet can serve as acceptor of electrons Registry number: EC 1.- (26 Jun 1999) |
| gaba modulators | Substances that do not act as agonists or antagonists but do affect the gaba receptor-ionophore complex. Gaba-a receptors (receptors, gaba-a) appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gaba-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. General anaesthetics probably act at least partly by potentiating gabaergic responses, but they are not included here. (12 Dec 1998) |
Synonyms : GABA Agonist, GABA Receptor Agonist, GABA Receptor Agonists, gamma-Aminobutyric Acid Agonist, Acid Agonist, gamma-Aminobutyric, Acid Agonists, gamma-Aminobutyric, Agonist, GABA, Agonist, GABA Receptor, Agonist, gamma-Aminobutyric Acid, Agonists, GABA
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