| free | 1. Exempt from subjection to the will of others; not under restraint, control, or compulsion; able to follow one's own impulses, desires, or inclinations; determining one's own course of action; not dependent; at liberty. "That which has the power, or not the power, to operate, is that alone which is or is not free." (Locke) 2. Not under an arbitrary or despotic government; subject only to fixed laws regularly and fairly administered, and defended by them from encroachments upon natural or acquired rights; enjoying political liberty. 3. Liberated, by arriving at a certain age, from the control of parents, guardian, or master. 4. Not confined or imprisoned; released from arrest; liberated; at liberty to go. "Set an unhappy prisoner free." (Prior) 5. Not subjected to the laws of physical necessity; capable of voluntary activity; endowed with moral liberty; said of the will. "Not free, what proof could they have given sincere Of true allegiance, constant faith, or love." (Milton) 6. Clear of offense or crime; guiltless; innocent. "My hands are guilty, but my heart is free." (Dryden) 7. Unconstrained by timidity or distrust; unreserved; ingenuous; frank; familiar; communicative. "He was free only with a few." (Milward) 8. Unrestrained; immoderate; lavish; licentious; used in a bad sense. "The critics have been very free in their censures." (Felton) "A man may live a free life as to wine or women." (Shelley) 9. Not close or parsimonious; liberal; open-handed; lavish; as, free with his money. 10. Exempt; clear; released; liberated; not encumbered or troubled with; as, free from pain; free from a burden; followed by from, or, rarely, by of. "Princes declaring themselves free from the obligations of their treaties." (Bp. Burnet) 11. Characteristic of one acting without restraint; charming; easy. 12. Ready; eager; acting without spurring or whipping; spirited; as, a free horse. 13. Invested with a particular freedom or franchise; enjoying certain immunities or privileges; admitted to special rights; followed by of. "He therefore makes all birds, of every sect, Free of his farm." (Dryden) 14. Thrown open, or made accessible, to all; to be enjoyed without limitations; unrestricted; not obstructed, engrossed, or appropriated; open; said of a thing to be possessed or enjoyed; as, a free school. "Why, sir, I pray, are not the streets as free For me as for you?" (Shak) 15. Not gained by importunity or purchase; gratuitous; spontaneous; as, free admission; a free gift. 16. Not arbitrary or despotic; assuring liberty; defending individual rights against encroachment by any person or class; instituted by a free people; said of a government, institutions, etc. 17. Certain or honorable; the opposite of base; as, free service; free socage. 18. Privileged or individual; the opposite of common; as, a free fishery; a free warren. 19. Not united or combined with anything else; separated; dissevered; unattached; at liberty to escape; as, free carbonic acid gas; free cells. Free agency, the capacity or power of choosing or acting freely, or without necessity or constraint upon the will. Free bench, to sail with the yards not braced in as sharp as when sailing closehauled, or close to the wind. Origin: OE. Fre, freo, AS. Freo, fri; akin to D. Vrij, OS. & OHG. Fri, G. Frei, Icel. Fri, Sw. & Dan. Fri, Goth. Freis, and also to Skr. Prija beloved, dear, fr. Pri to love, Goth. Frijn. Cf. Affray, Belfry, Friday, Friend, Frith inclosure. Source: Websters Dictionary (01 Mar 1998) |
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| free association | Spontaneous verbalization of whatever comes to mind. (12 Dec 1998) |
| free bone flap | Portion of cranium removed and detached from overlying soft tissue structures. (05 Mar 2000) |
| free border | Unattached edge of a sturcture, often opposite the attached edge. See: free border of nail, free border of ovary. Synonym: margo liber, free margin. (05 Mar 2000) |
| free border of nail | The distal border of the nail that overhangs the tip of the digit. Synonym: margo liber unguis. (05 Mar 2000) |
| free border of ovary | The unattached, posterior margin of the ovary. Synonym: margo liber ovarii. (05 Mar 2000) |
| free calcium level | <biochemistry> The ionised calcium represents the calcium (Ca++) that is the metabolically active calcium. Normal values for ionised calcium in the bloodstream should be 4.4 to 5.3 mg/dl for adults and 4.4 to 6.0 mg/dl for children. Elevations may be seen in hyperparathyroidism, metastatic bone tumour, milk-alkali syndrome, multiple myeloma, Paget's disease, sarcoidosis, PTH-secreting tumours (paraneoplastic syndrome) and vitamin D intoxication. Lower than normal values may be seen in hypoparathyroidism, malabsorption, osteomalacia, pancreatitis, renal failure, rickets and vitamin D deficiency. (27 Sep 1997) |
| free electron | <radiobiology> An electron not bound to an atom, molecule, or other particle via electromagnetic forces. (09 Oct 1997) |
| free electrophoresis | Electrophoresis of substances placed in a solution in a U-shaped tube. (05 Mar 2000) |
| free energy | A thermodynamic term used to describe the energy that may be extracted from a system at constant temperature and pressure. In biological systems the most important relationship is: _G = RTln(Keq), where Keq is an equilibrium constant. (18 Nov 1997) |
| free field | A field (three-dimensional space) in a homogeneous, isotropic medium free from boundaries; in practice, a field in which boundary effects are negligible. (05 Mar 2000) |
| free flap | Island flap in which the donor vessels are severed proximally, the flap is transported as a free object to the recipient area, and the flap is revascularised by anastomosing its supplying vessels to vessels there. (05 Mar 2000) |
| free gingiva | That portion of the gingiva that surrounds the tooth and is not directly attached to the tooth surface; the outer wall of the gingival sulcus. (05 Mar 2000) |
| free graft | A graft transplanted without its normal attachments, or a pedicle, from one site to another. (05 Mar 2000) |
| free induction decay | In magnetic resonance imaging, the decay curve that is detected by the radiofrequency coil after the application of an excitation pulse, without additional pulses (free). (05 Mar 2000) |
| bacteria-free stage of bacterial endocarditis | Endocarditis described prior to the antibiotic era and presumably due to spontaneous healing of the bacterial vegetations. (05 Mar 2000) |
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| carbon dioxide-free water | Purified water that has been boiled vigorously for 5 minutes or more. (05 Mar 2000) |
| radical, free | In biochemistry, it is a group of atoms bonded together into an entity that is extremely reactive and shortlived. (a free radical is not a political extremist on parole.) (12 Dec 1998) |
| germ-free animal | An animal which has no microorganisms whatsoever living in or on it. An animal which was born and raised in an isolated environment with no microorganisms in it, such as within a germ-free isolator. (09 Oct 1997) |
| germ-free isolator | A chamber which has absolutely no microorganisms whatsoever living in it, where a germ-free animal can be born and raised. An artificial barrier surrounding a living facility for germ-free animals, which keeps out all microorganisms. (09 Oct 1997) |
| germ-free life | Animals not contaminated by or associated with any foreign organisms. (12 Dec 1998) |
| carrier-free | A substance in which a radioactive or other tagged atom is found in every molecule; the highest possible specific activity. (05 Mar 2000) |
| gibbs free energy | The total amount of energy which is either used up or released during a chemical reaction. Gibbs free energy (delta G) = (delta H) - t (delta s): where (delta H) is the change in enthalpy, calculated by adding up the amount of energy released or used up to break or form chemical bonds during the reaction, t is the temperature at which the reaction took place, and (delta S) is the change in entropy, or amount of disorder, that occurs in the molecules involved during the reaction. (09 Oct 1997) |
| mean free path | <radiobiology> Average distance a particle travels between occurrences of the given event, for example, between collisions. For collisions, the mean free path is roughly equal to unity divided by the product of the collision cross-section times the particle density. (09 Oct 1997) |
| cell-free extract | <cell culture> A liquid that is a mixture of the contents of a particular type of cell, sometimes the organelles are also filtered out of the liquid. (26 Mar 1998) |
| cell-free protein synthesis | <technique> An in vitro method to make proteins, using amino acids, the mRNA corresponding to the protein to be made, and a cell-free extract (the contents of a cell after removal of the cell wall and/or outer cell membranes) for other needed components and enzymes. (26 Mar 1998) |
| cell-free system | <cell culture, molecular biology> Any system in which a normal cellular reaction is reconstituted in the absence of cells for example in vitro translation systems that will synthesise protein from mRNA using a lysate of rabbit reticulocytes or wheat germ. A fractionated cell extract that maintains a biological function. A subcellular fraction isolated by ultracentrifugation or other separation techniques must first be isolated so that a process can be studied free from all of the complex side reactions that occur in a cell. The cell-free system is therefore widely used in cell biology. (12 Dec 1998) |
| gluten-free diet | Elimination of all wheat, rye, barley, and oat gluten from the diet; treatment for gluten-sensitive enteropathy (coeliac disease). See: coeliac disease. (05 Mar 2000) |
| working distance free | <microscopy> The distance between the front lens of the objective and the coverslip (or uncovered object) when the lens is focused on the specimen. (05 Aug 1998) |
| culture media, serum-free | Culture media free of serum proteins but including the minimal essential substances required for cell growth. This type of medium avoids the presence of extraneous substances that may affect cell proliferation or unwanted activation of cells. (12 Dec 1998) |