| frameshift | <molecular biology> A shift in the reading frame used to translate the base sequence of DNA or mRNA. It is caused by the addition or deletion of one or more of the bases, resulting in an alternative peptide being formed. (17 Dec 1997) |
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| frameshift mutagen | <molecular biology> A mutagen, such as an acridine derivative, that causes a frameshift mutation; codons (base triplets) are read out of phase and different amino acids are made. (05 Mar 2000) |
| frameshift mutation | <molecular biology> A type of mutation that results from insertion or deletion of a single nucleotide into, or from, an open reading frame in the normal DNA sequence. Normally, the genetic code is read in the wrong frame, three nucleotides at a time, and the entire sequence downstream of the mutation, is translated into a polypeptide with a garbled amino acid sequence from the mutated codon onwards. These mutations may be induced by certain types of mutagens or may occur spontaneously and usually result in the generation, downstream, of nonsense, chain termination codons. Synonym: addition mutation, addition-deletion mutation, deletion mutation, reading-frameshift mutation. (21 Jun 2000) |
| frameshifting, ribosomal | A directed change in translational reading frame that allows the production of a single protein from two or more overlapping genes. The process is programmed by the nucleotide sequence of the mRNA and is sometimes also affected by the secondary or tertiary mRNA structure. It has been described mainly in viruses (especially retroviruses), retrotransposons, and bacterial insertion elements but also in some cellular genes. (12 Dec 1998) |
| reading-frameshift mutation | <molecular biology> A type of mutation that results from insertion or deletion of a single nucleotide into, or from, an open reading frame in the normal DNA sequence. Normally, the genetic code is read in the wrong frame, three nucleotides at a time, and the entire sequence downstream of the mutation, is translated into a polypeptide with a garbled amino acid sequence from the mutated codon onwards. These mutations may be induced by certain types of mutagens or may occur spontaneously and usually result in the generation, downstream, of nonsense, chain termination codons. Synonym: addition mutation, addition-deletion mutation, deletion mutation, reading-frameshift mutation. (21 Jun 2000) |
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Synonyms : Frame Shift Mutation, Out-of-Frame Deletion, Out-of-Frame Mutation, Deletion, Out-of-Frame, Deletions, Out-of-Frame, Frame Shift Mutations, Frameshift Mutations, Mutation, Frame Shift, Mutation, Out-of-Frame, Mutations, Frame Shift, Mutations, Frameshift
Synonyms : Ribosomal Frame Shift, Ribosomal Frame Shifting, Ribosomal Frameshift, Frame Shift, Ribosomal, Frame Shifting, Ribosomal, Frame Shifts, Ribosomal, Frameshift, Ribosomal, Frameshifts, Ribosomal, Ribosomal Frame Shifts, Ribosomal Frameshifts
| frameshift mutation |
FRAME-shift mew-TAY-shun A mutation that adds or deletes one or two DNA bases, altering the reading frame. 341
출처: www.mhhe.com/biosci/genbio/life/glossaryf.mhtml
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| frameshift mutation |
An alteration of DNA where insertion or deletion of sequence occurs that is not a multiple of three base pairs, thus disrupting the gene/protein뭩 normal code.
출처: www.knowledgene.com/public/glossary_content.php3
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| frameshift mutation |
an alteration in the reading frame of a gene due to the insertion or deletion of one or more base pairs (but not a multiple of three); frameshift mutations usually lead to nonfunctional proteins.
출처: www-hsc.usc.edu/~dconti/notes/genetic_terms.htm
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| frameshift m. |
a mutation resulting from an addition or subtraction that is not an exact multiple of 3 base pairs in a coding sequence. From the point of mutation onwards, base triplets (codons) are read out of phase; the reading frame of the gene is changed, and a completely different set of amino acids is made into protein. Called also reading frameshift m.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| frameshift mutation |
The insertion or deletion of nucleotides in the coding region of a gene causes the reading fram to shift. Shifting of the reading fram results in a change in the translation of the mRNA transcript. Therefore, a one or two base change results in a frameshift, while a three base change does not shift the reading frame, but can change the amino acid added by that codon (see missense mutation)
출처: pathology2.jhu.edu/molec/glossary.cfm
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제품명 |
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보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
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보험코드 | 성분/함량 | 구분/보험급여 |
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