| frameshift mutation |
FRAME-shift mew-TAY-shun A mutation that adds or deletes one or two DNA bases, altering the reading frame. 341
출처: www.mhhe.com/biosci/genbio/life/glossaryf.mhtml
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| frameshift mutation |
An alteration of DNA where insertion or deletion of sequence occurs that is not a multiple of three base pairs, thus disrupting the gene/protein뭩 normal code.
출처: www.knowledgene.com/public/glossary_content.php3
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| frameshift mutation |
an alteration in the reading frame of a gene due to the insertion or deletion of one or more base pairs (but not a multiple of three); frameshift mutations usually lead to nonfunctional proteins.
출처: www-hsc.usc.edu/~dconti/notes/genetic_terms.htm
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| frameshift m. |
a mutation resulting from an addition or subtraction that is not an exact multiple of 3 base pairs in a coding sequence. From the point of mutation onwards, base triplets (codons) are read out of phase; the reading frame of the gene is changed, and a completely different set of amino acids is made into protein. Called also reading frameshift m.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| frameshift mutation |
The insertion or deletion of nucleotides in the coding region of a gene causes the reading fram to shift. Shifting of the reading fram results in a change in the translation of the mRNA transcript. Therefore, a one or two base change results in a frameshift, while a three base change does not shift the reading frame, but can change the amino acid added by that codon (see missense mutation)
출처: pathology2.jhu.edu/molec/glossary.cfm
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