| fragile site |
Chromosomal anomaly that appears as a region of decondensed or partially broken mitotic chromosomes under specific karyotyping conditions. The FRAXA and FRAXE fragile sites contain expanded CGG repeats that are methylated, affecting the expression of the FMR1 and FMR2 genes, respectively.
출처: www.nature.com/nrg/journal/v2/n9/glossary/nrg0901_...
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| fragile site |
A chromosomal region that has a tendency to break.
출처: helios.bto.ed.ac.uk/bto/glossary/ef.htm
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| fragile site |
A small break or a constriction of a chromosome that can be visualised after special treatment of the chromosomes. In individuals affected with fragile X syndrome, a fragile site can often be seen on their X chromosome.
출처: www.agsa-geneticsupport.org.au/glossary.html
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