| fragile X syndrome |
Fragile X Syndrome is the most common inherited cause of mental impairment, and the most common known cause of autism. Fragile X syndrome is a genetic disorder caused by a mutation of the FMR1 gene on the X chromosome, a mutation found in 1 out of every 2000 males and 1 out of every 4000 females. Typically the FMR1 gene contains between 6 and 53 repeats of the CGG codon. In people with the disorder, the FMR1 allele has over 230 repeats. ...
출처: en.wikipedia.org/wiki/Fragile_X_syndrome
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| fragile site |
Chromosomal anomaly that appears as a region of decondensed or partially broken mitotic chromosomes under specific karyotyping conditions. The FRAXA and FRAXE fragile sites contain expanded CGG repeats that are methylated, affecting the expression of the FMR1 and FMR2 genes, respectively.
출처: www.nature.com/nrg/journal/v2/n9/glossary/nrg0901_...
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| fragile site |
A chromosomal region that has a tendency to break.
출처: helios.bto.ed.ac.uk/bto/glossary/ef.htm
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| fragile X syndrome |
The commonest cause of severe mental retardation in males, caused by a long
출처: www.jansen.com.au/Dictionary_DF.html
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| fragile X syndrome |
a syndrome resulting from a fragile or broken site on the X chromosome, often characterized by mental retardation, hypotonia and hyperactivity
출처: depts.washington.edu/pwdlearn/web/glossary/glossar...
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