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radio label A mildly radioactive molecule that is used to tag another molecule (such as a protein) so that it can be identified as it goes through some kind of biochemical process.
(09 Oct 1997)
chromogenic label A molecule which can be used as a label to a biological probe molecule because it forms a coloured compound when the probe molecule is attached to its target.
(09 Oct 1997)
off-label Use of a drug for a disease or condition other than the indication for which it was approved by the FDA. For example: many doctors prescribe paromomycin (humatin) for cryptosporidiosis, although it is not approved for treating this disease.
(09 Oct 1997)
off-label use In the United States, the regulations of the Food and drug administration (FDA) permit physicians to prescribe approved medications for other than their intended indications. This practice is known as off-label use.
(12 Dec 1998)
open-label trial A study in which both researchers and participants know what drug a person is taking and at what dose.
(09 Oct 1997)
label 1. To incorporate into a compound a substance that is readily detected, such as a radionuclide, whereby its metabolism can be followed or its physical distribution detected.
2. The substance so incorporated.
(05 Mar 2000)
fluorescent label A molecule which fluoresces and can be attached to a probe molecule that does not fluoresce.
(09 Oct 1997)
apophysial fracture Separation of apophysis from bone.
(05 Mar 2000)
articular fracture A fracture involving the joint surface of a bone.
(05 Mar 2000)
atlas fracture <radiology> Incidence: 4% of cervical spine injuries, site: posterior arch, anterior arch, massa lateralis, Jefferson fracture associated with: fractures of C7 (25%), fractures of C2 pedicle (15%), extraspinal fractures (58%)
(12 Dec 1998)
avulsion fracture A fracture that occurs when a joint capsule, ligament, or muscle insertion of origin is pulled from the bone as a result of a sprain dislocation or strong contracture of the muscle against resistance; as the soft tissue is pulled away from the bone, a fragment or fragments of the bone may come away with it.
(05 Mar 2000)
axis fracture <radiology> Incidence: 6% of cervical spine injuries, associated with atlas fractures in 8%, hyperflexion injury: odontoid fracture, type I avulsion of tip of odontoid (5-8%) difficult to detect, type II fracture through base of dens (54-67%) complication: nonunion, type III subdental injury (30-33%) prognosis: good, Differential diagnosis: os odontoideum, ossiculum terminale, hypoplasia/aplasia of dens, hyperextension injury: hangman's fracture
(12 Dec 1998)
barton fracture <radiology> Intra-articular fracture of distal radius, dorsal displacement of separated fragment, due to fall on outstretched hand see: wrist fractures
(12 Dec 1998)
Barton's fracture Fracture of the distal radius with dislocation of the radiocarpal joint.
(05 Mar 2000)
basal skull fracture <orthopaedics> A fracture involving the base of the cranium.
This fracture is often difficult to detect clinically. Findings may include raccoon eyes, Battle's sign, haemotympanum and cerebrospinal fluid rhinorrhoea.
Plain skull X-ray will often not reveal the basal skull fracture, making a CT scan or MRI the most reliable diagnostic investigation.
(15 Nov 1997)
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