| formyltetrahydrofolate |
any derivative of tetrahydrofolate that carries a formyl group substitution. The 5-formyl derivative is folinic acid (q.v.); the 10-formyl derivative is important in purine synthesis and in the liver-mediated release of excess one-carbon units.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| formyltetrahydrofolate dehydrogenase |
[EC 1.5.1.6] an enzyme of the oxidoreductase class that catalyzes the oxidative decarboxylation of 10-formyltetrahydrofolate to produce tetrahydrofolate, using NADP+as an electron acceptor. The reaction occurs in liver to release excess active one-carbon fragments and maintain sufficient tetrahydrofolate for metabolism.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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