| formyltetrahydrofolate deformylase | <enzyme> From rat or pig liver homogenates; catalyses the conversion of 10-formyltetrahydrofolate to tetrahydrofolate and formate; amino acid sequence has been determined Registry number: EC 3.5.1.10 Synonym: formyltetrahydrofolate hydrolase, 10-formyltetrahydrofolate amidohydrolase, fthf hydrolase, puru protein, puru gene product (26 Jun 1999) |
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| formyltetrahydrofolates | Tetrahydrofolates which are substituted by a formyl group at either the nitrogen atom in the 5 position or the nitrogen atom in the 10 position. N(5)-formyltetrahydrofolate is leukovorin (citrovorum factor) while n(10)-formyltetrahydrofolate is an active coenzyme which functions as a carrier of the formyl group in a number of enzymatic reactions. (12 Dec 1998) |
| N10-formyltetrahydrofolate | A formyl derivative of tetrahydrofolate that serves as a one-carbon source in metabolism. (05 Mar 2000) |
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Synonyms : Acids, Formyltetrahydrofolic
| formyltetrahydrofolate |
any derivative of tetrahydrofolate that carries a formyl group substitution. The 5-formyl derivative is folinic acid (q.v.); the 10-formyl derivative is important in purine synthesis and in the liver-mediated release of excess one-carbon units.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| formyltetrahydrofolate dehydrogenase |
[EC 1.5.1.6] an enzyme of the oxidoreductase class that catalyzes the oxidative decarboxylation of 10-formyltetrahydrofolate to produce tetrahydrofolate, using NADP+as an electron acceptor. The reaction occurs in liver to release excess active one-carbon fragments and maintain sufficient tetrahydrofolate for metabolism.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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