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| EF | ectopic focus; edema factor; ejection fraction; elastic fibril; electric field; elongation factor; e... |
|---|---|
| EU | Ehrlich unit; elementary unit; emergency unit; endotoxin unit; entropy unit; enzyme unit; esterase u... |
| CU | cardiac unit; casein unit; cause unknown or undetermined; chymotrypsin unit; clinical unit; color un... |
| CFU-S, | CFUS colony-forming unit, spleen; colony-forming unit, stem cells |
| PFU | plaque-forming unit; pock-forming unit |
| SFFV | Spleen Focus Forming virus |
|---|---|
| FFU | focus forming units |
| MCF | mink cell focus forming |
| SFFVP | spleen focus-forming virus |
| PFU | Plaque Forming Unit |
| focus-forming unit | A measurement of the concentration of live virus in a given amount of fluid. This is measured by spreading a known amount of the fluid over a layer of cultured cells which are infected by the virus, then counting the number of areas in the culture which look infected. (09 Oct 1997) |
|---|---|
| spleen focus-forming viruses | Murine leukaemia viruses that are replication-defective and rapidly transforming. The envelope gene plays an essential role in initiating erythroleukaemia, manifested by splenic foci, splenomegaly, and polycythemia. Spleen focus-forming viruses are generated by recombination with other viral types including friend p (polycythemia), friend a (anaemia), rauscher, and cas (from wild mice at lake casita, california). (12 Dec 1998) |
| focus-forming assay | <investigation> A lab technique used to find out if a particular piece of DNA contains oncogenes (genes which are associated with cancer). This is done by putting the DNA into animal cells which normally show contact inhibition, or which stop growing when they come into physical contact with other cells or reach a certain density in the culture. If the cells lose contact inhibition and form areas of densely-packed cells (called foci) after receiving the DNA, it means that the DNA did contain oncogenes. (05 Jan 1997) |
| Friend spleen focus forming virus | <virology> Defective virus found in certain strains of Friend virus, detected by its ability to form foci in spleens of mice and believed to be responsible in those strains for the production of a leukaemia associated with polycythaemia rather than anaemia. (18 Nov 1997) |
| burst forming unit | <haematology> A bone marrow stem cell lineage detected in culture by its mitotic response to erythropoietin and subsequent erythrocytic differentiation in about 12 mitotic cycles into erythrocytes. (18 Nov 1997) |
| colony-forming unit | <cell biology> An individual cell which is able to clone itself into an entire colony of identical cells. Irradiated mice can have their immune systems reconstituted by the injection of bone marrow cells from a nonirradiated animal. The injected cells form colonies in the spleen (hence s), each colony representing the progeny of a pluripotent stem cell. Operationally, therefore, the number of colony-forming units is a measure of the number of stem cells. Acronym: CFU (09 Oct 1997) |
| plaque-forming unit | <virology> Number of infectious virus particles or Ig producing cells per unit volume. See: plaque assay. <microbiology> Refers to any entity which can give rise to a plaque. For example: if a phage stock solution has 1010 pfu/ml, it means that every ml of this stock has 1010 phage particles which can form plaques. This (pfu/ml) is the conventional way to refer the concentration of a phage preparation. Compare: CFU. (10 Oct 1997) |
| real focus | The point of meeting of convergent rays. (05 Mar 2000) |
| Ghon's focus | Calcification seen in pulmonary parenchyma (usually mid-lung area) and hilar nodes resulting from earlier, usually childhood, infection with tuberculosis. Synonym: Ghon's complex, Ghon's focus, Ghon's primary lesion. (05 Mar 2000) |
| virtual focus | The point from which divergent rays seem to proceed, or that at which they would meet if prolonged backward. (05 Mar 2000) |
| mink cell focus-inducing viruses | Murine leukaemia viruses discovered in 1976 by hartley, wolford, old, and rowe and so named because the viruses originally isolated had the capacity to transform cell foci in mink cell cultures. Mcf viruses are generated in a multi-step process by recombination with other viral types including akr, friend, moloney, and rauscher. (12 Dec 1998) |
| plasma focus | <radiobiology> The Plasma Focus is another device which depends on the pinch effect. Possible applications include both fusion and plasma propulsion, as well as other plasma research. In essence the plasma focus is generated by discharge of a current across the ends of two coaxial insulated conducting pipes. The Plasma Focus caused a huge stir when they generated copious neutrons, until it was discovered that the source of the neutrons was knockoffs from deuterium due to pinch accelerated electrons or ions. Plasma focus is sort of a point version of the Zpinch. (09 Oct 1997) |
| condenser, variable-focus | <microscopy> Essentially an Abbe condenser in which the upper lens element is fixed and the lower movable. The lower lens may be used to focus the illumination between the elements so that it emerges from the stationary lens as a large diameter parallel bundle. The field of low-power objectives may thus be filled without removing the top element. at the opposite extreme it can be adjusted to have a numerical aperture as high as 1.3. See: illumination, critical. (05 Aug 1998) |
| principal focus | The real or virtual meeting point of rays passing into a lens parallel to its axis. (05 Mar 2000) |
| natural focus of infection | An ecosystem in which an infectious agent normally persists in nature; e.g., yellow fever virus in a jungle monkey-Haemagogus mosquito ecosystem. (05 Mar 2000) |
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