| DLI | distolinguoincisal; double label index |
|---|---|
| FA | false aneurysm; Families Anonymous; Fanconi anemia; far advanced; fatty acid; febrile antigen; femor... |
| FAT | family attitudes test; fluorescent antibody technique; fluorescent antibody test |
| FTA | fluorescent titer antibody; fluorescent treponemal antibody |
| IFA | idiopathic fibrosing alveolitis; immunofluorescence assay; immunofluorescent antibody; incomplete Fr... |
| GFP | 1-green fluorescent protein |
|---|---|
| DFA | Direct Fluorescent Antibody |
| EGFP | Enhanced Green Fluorescent Protein |
| Fl- | Fluorescent |
| FACS | Fluorescent Activated Cell Sorter |
| fluorescent label | A molecule which fluoresces and can be attached to a probe molecule that does not fluoresce. (09 Oct 1997) |
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| radio label | A mildly radioactive molecule that is used to tag another molecule (such as a protein) so that it can be identified as it goes through some kind of biochemical process. (09 Oct 1997) |
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| chromogenic label | A molecule which can be used as a label to a biological probe molecule because it forms a coloured compound when the probe molecule is attached to its target. (09 Oct 1997) |
| off-label | Use of a drug for a disease or condition other than the indication for which it was approved by the FDA. For example: many doctors prescribe paromomycin (humatin) for cryptosporidiosis, although it is not approved for treating this disease. (09 Oct 1997) |
| off-label use | In the United States, the regulations of the Food and drug administration (FDA) permit physicians to prescribe approved medications for other than their intended indications. This practice is known as off-label use. (12 Dec 1998) |
| open-label trial | A study in which both researchers and participants know what drug a person is taking and at what dose. (09 Oct 1997) |
| label | 1. To incorporate into a compound a substance that is readily detected, such as a radionuclide, whereby its metabolism can be followed or its physical distribution detected. 2. The substance so incorporated. (05 Mar 2000) |
| auramine O fluorescent stain | <technique> A rapid and accurate technique for Mycobacterium tuberculosis, using auramine O-phenol and a methylene blue counterstain. (05 Mar 2000) |
| green fluorescent protein | <protein> A protein found in jellyfish which fluoresces, or glows green visible light when excited by UV light with a wavelength of 395 nanometres. It can function as a biological marker when attached to other proteins. The structure of the protein is cylindrical with the glowing component, an amino acid complex called a fluorophore, in the middle of it. (09 Oct 1997) |
| microscope, fluorescent | A microscope equipped to examine material that fluoresces under ultraviolet (uv) light. (12 Dec 1998) |
| direct fluorescent antibody | The straightforward detection of antigens using fluorescent labelled antigen-specific antibody. Because detection of the antigen in a substrate of patient sample (cellular smear, fluid or patient-inoculated culture medium) is the goal, direct fluorescent antibody is seldom quantitative. (05 Mar 2000) |
| direct fluorescent antibody test | Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (fluorescent antibody technique, direct) or an indirect method, by formation of antigen-antibody complex which is then labelled with fluorescein-conjugated anti-immunoglobulin antibody (fluorescent antibody technique, indirect). The tissue is then examined by fluorescence microscopy. (12 Dec 1998) |
| indirect fluorescent antibody | The detection of antibodies to specific antigenic material in the substrate using fluorescent microscopy. Using fluorescent conjugated antibodies which are specific for a particular isotype of antibody, it is possible to distinguish IgG, IgA and IgM isotypes of specific antibodies using indirect fluorescent antibody. This sensitive technique is highly specific in well-trained hands and recent developments in the establishment of internationally recognised standard materials have led to accurate quantitation of antibody concentrations through endpoint titration (the highest serial dilution of specimen at which specific fluorescence remains) and through measuring visual intensity of fluorescence compared to known reference standard material. (05 Mar 2000) |
| Kasten's fluorescent Feulgen stain | <technique> A fluorescent modification of the Feulgen stain, utilizing any one of a variety of fluorescent basic dyes to which SO2 is added; the brilliant fluorescence makes this method unusually sensitive and adaptable to cytofluorometric quantification of DNA. (05 Mar 2000) |
| Kasten's fluorescent PAS stain | <technique> A fluorescent modification of the periodic acid Schiff stain for polysaccharides which uses one of Kasten's fluorescent Schiff reagents. (05 Mar 2000) |
| Kasten's fluorescent Schiff reagents | Fluorescent analogues of Schiff's reagent which are fluorescent basic dyes lacking acidic side groups and containing one or more primary amine groups; used in cytochemical detection of DNA in Kasten's fluorescent Feulgen stain, polysaccharides in Kasten's fluorescent PAS stain, and proteins in the ninhydrin-Schiff stain; such analogues include acriflavine, auramine O, and flavophosphine N. (05 Mar 2000) |
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