| FN | false negative; fibronectin; fluoride number |
|---|---|
| FNL | fibronectin-like |
| FNR | fibronectin receptor |
| FNRA | fibronectin receptor alpha |
| FNRB | fibronectin receptor beta |
| cFN | Cellular fibronectin |
|---|---|
| fFN | Fetal fibronectin |
| FN | Fibronectin |
| FnBP | Fibronectin binding proteins |
| FN-R | fibronectin receptor |
| fibronectin | <protein> Glycoprotein of high molecular weight (2 chains each of 250 kD linked by disulphide bonds) that occurs in insoluble fibrillar form in extracellular matrix of animal tissues and soluble in plasma, the latter previously known as cold insoluble globulin. The various slightly different forms of fibronectin appear to be generated by tissue specific differential splicing of fibronectin mRNA, transcribed from a single gene. Fibronectins have multiple domains that confer the ability to interact with many extracellular substances such as collagen, fibrin and heparin and also with specific membrane receptors on responsive cells. Notable is the RGD domain recognised by integrins and two repeats of the EGF like domain. Interaction of a cells fibronectin receptors (members of the integrin family) with fibronectin adsorbed to a surface results in adhesion and spreading of the cell. (18 Nov 1997) |
|---|---|
| fibronectin hexapeptide N-acetylgalactosaminyltransferase | <enzyme> Enzyme from foetal and malignant tissues recognizing the sequence val-thr-his-pro-gly-tyr in fibronectin Registry number: EC 2.4.1.- Synonym: udp-galnac-vthpgy alpha-galnac transferase, hexapeptide-galnac-transferase (26 Jun 1999) |
| fibronectin laminase | <enzyme> Fibronectin fragment which has been activated by calcium chloride to produce a calcium-dependent proteolytic activity that splits preferentially laminin and denatured collagen type 1; cleaves the ala-gly bond in the sequence gpagpr; the arginine residue in position p3' is important for this cleavage Registry number: EC 3.4.99.- Synonym: fn-laminase (26 Jun 1999) |
| fibronectinase | <enzyme> Generated from a 27kda n-terminal heparin-binding fragment of fibronectin; calcium-dependent Registry number: EC 3.4.21.- (26 Jun 1999) |
| fibronectins | Glycoproteins found on the surfaces of cells, particularly in fibrillar structures. The proteins are lost or reduced when these cells undergo viral or chemical transformation. They are highly susceptible to proteolysis and are substrates for activated blood coagulation factor viii. The forms present in plasma are called cold-insoluble globulins. (12 Dec 1998) |
| receptors, fibronectin | Specific sites or molecular structures on or in cells with which fibronectins react or to which they bind. Studies have shown that these receptors function in certain types of adhesive contact as well as playing a major role in matrix assembly. These are the traditional fibronectin receptors, also called vla-5 receptors or alpha 5 beta 1 integrins. There are also other integrins that bind fibronectin, including alpha v beta 1. (12 Dec 1998) |
|---|---|
| plasma fibronectin | A circulating a2-glycoprotein that functions as an opsonin, mediating reticuloendothelial and macrophage clearance of fibrin microaggregates, collagen debris, and bacterial particulates, protecting microvascular perfusion and lymphatic drainage. (05 Mar 2000) |
Synonyms : Fibronectin, Opsonic Glycoprotein, Opsonic alpha(2)SB Glycoprotein, alpha 2-Surface Binding Glycoprotein, Cold Insoluble Globulins, Globulins, Cold-Insoluble, Glycoprotein, Opsonic, Proteins, LETS, alpha 2 Surface Binding Glycoprotein
| fibronectin |
a substance found in and around the amiotic sac (that is, the fetal membranes or bag of waters). Fibronectin may serve as a glue in and the cells of the fetal membranes. Fibronectin is released in large amounts when a woman goes into labor. It is currently being used as the basis of a test to diagnosis inevitable premature birth.
Ãâó: www.abcbirth.com/lGlossary.html
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|---|---|
| fibronectin |
proteins recognized by integrins to interact with collagen
Ãâó: student.biology.arizona.edu/honors2000/group10/Glo...
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| fibronectin |
Glycoprotein of high molecular weight (2 chains each of 250 kD linked by disulphide bonds) that occurs in insoluble fibrillar form in extracellular matrix of animal tissues, and soluble in plasma, the latter previously known as cold-insoluble globulin. The various slightly different forms of fibronectin appear to be generated by tissue-specific differential splicing of fibronectin mRNA, transcribed from a single gene. ...
Ãâó: worms.zoology.wisc.edu/urchins/SUglossary.html
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| fibronectin |
A plasma protein. As is true for all proteins, regardless of their origin, it is a good water-binding agent for skin.
Ãâó: www.paulaschoice.com.au/dictionary/dict2.htm
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