| ferrochelatase |
[EC 4.99.1.1] a mitochondrial enzyme of the lyase class that catalyzes the insertion of ferrous iron into protoporphyrin IX to form protoheme IX, the heme of hemoglobin. Inhibition of the enzyme in lead poisoning results in accumulation of protoporphyrin IX. Deficiency of the enzyme, an autosomal dominant trait, results in protoporphyria.
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