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photoaffinity labelling <technique> A technique for covalently attaching a label or marker molecule onto another molecule such as a protein.
The label, which is often fluorescent or radioactive, contains a group that becomes chemically reactive when illuminated usually with ultraviolet light) and will form a covalent linkage with an appropriate group on the molecule to be labelled: proximity is essential. The most important class of photoreactive groups used are the aryl azides, which form short lived but highly reactive nitrenes when illuminated.
(31 Dec 1997)
spin labelling <chemistry, technique> The technique of introducing a grouping with an unpaired electron to act as an electron spin resonance (ESR) reporter species. This is almost invariably a nitroxide compound (N O) in which the nitrogen forms part of a sterically hindered ring.
(18 Nov 1997)
drug labelling Use of written, printed, or graphic materials upon or accompanying a drug container or wrapper. It includes contents, indications, effects, dosages, routes, methods, frequency and duration of administration, warnings, hazards, contraindications, side effects, precautions, and other relevant information.
(12 Dec 1998)
cationised ferritin <chemical> Ferritin, treated with dimethyl propanediamine and used to show, in the electron microscope, the distribution of negative charge on the surface of a cell.
The amount of cationic ferritin binding is very approximately related to the surface charge.
(16 Mar 1998)
serum ferritin <protein> A test that measures the amount of ferritin, a major iron storage protein. This test reflects the amount of iron stored in the body. Higher than normal values can be seen in haemochromatosis. Normal values for males: 12 to 300 ng/ml, females: 10 to 150 ng/ml.
(27 Sep 1997)
ferritin <protein> An iron storage protein of mammals, found in liver, spleen and bone marrow.
Morphologically a shell of apoferritin protein with a core of ferrous hydroxide or phosphate. It is much used as an electron dense label in electron microscopy.
(18 Nov 1997)
ferritin reductase <enzyme> Requires fmn
Registry number: EC 1.6.99.-
Synonym: ferriductase
(26 Jun 1999)
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