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  • erythroblastic anemia
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  • erythroblastic anemia
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  • erythroblastic shower
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  • erythroblastic anemia
    Àû¸ð±¸¼º ºóÇ÷.
  • erythroblastic island
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  • erythroblastic shower
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  • familial erythroblastic anemia
    °¡Á·¼º Àû¸ð±¸¼º ºóÇ÷(¡­îåٽϹàõ
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EBI emetine bismuth iodide; erythroblastic island; estradiol binding index
EBL erythroblastic leukemia; estimated blood loss
CancerWEB ¿µ¿µ ÀÇÇлçÀü ¸ÂÃã °Ë»ö °á°ú : 1 ÆäÀÌÁö: 1
erythroblastic anaemia Anaemia characterised by the presence of large numbers of nucleated red cells (normoblasts and erythroblasts) in the peripheral blood. Seen especially in newborns with haemolytic anaemia, such as that caused by Rh or ABO incompatibility.
Synonym: erythroblastic anaemia.
(05 Mar 2000)
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primary erythroblastic anaemia The dire disease also known as beta thalassaemia. The clinical picture of this form of anaemia was first described in 1925 by the paediatrician thomas benton cooley. Other names for the disease are cooley's anaemia and mediterranean anaemia. The term thalassaemia was coined by the nobel prise winning pathologist george whipple and the professor of paediatrics william bradford at u. Of rochester because thalassa in greek means the sea (like the mediterrranean sea) + -aemia means in the blood so thalassaemia means sea in the blood. Thalassaemia is not just one disease. It is a complex contingent of genetic (inherited) disorders all of which involve underproduction of haemoglobin, the indispensable molecule in red blood cells that carries oxygen. The globin part of normal adult haemoglobin is made up of 2 alpha and 2 beta polypeptide chains. In beta thalassaemia, there is a mutation (change) in both beta globin chains leading to underproduction (or absence) of beta chains, underproduction of haemoglobin, and profound anaemia. The gene for beta thalassaemia is relatively frequent in people of mediterranean origin (for example, from italy and greece). Children with this disease inherit one gene for it from each parent (and so are said to be homozygous for beta thalassaemia). The parents are carriers (heterozygotes) with just one thalassaemia gene, are said to have thalassaemia minor, and are essentially normal. Their children affected with beta thalassaemia seem entirely normal at birth (because at birth we still have predominantly foetal haemoglobin which does not contain beta chains) but the anaemia emerges in the first few months of life and becomes progressively more severe leading to pallor and easy fatiguability, failure to thrive (grow), bouts of fever (due to infections) and diarrhoea. Treatment based on blood transfusions is helpful but not curative. Gene therapy will, it is hoped, be applicable to this disease.
(12 Dec 1998)
familial erythroblastic anaemia An outmoded term for thalassaemia major.
(05 Mar 2000)
leukaemia, erythroblastic, acute A myeloproliferative disorder characterised by neoplastic proliferation of erythroblastic and myeloblastic elements with atypical erythroblasts and myeloblasts in the peripheral blood.
(12 Dec 1998)
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erythroblastic of, or relating to, erythroblasts.
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