| generalised epidermolytic hyperkeratosis | Diffusely red, eroded skin at birth, with subsequent scaling, tending to improve in later life, characterised by generalised epidermolytic hyperkeratosis and autosomal dominant inheritance. See: epidermolytic hyperkeratosis. Synonym: generalised epidermolytic hyperkeratosis, ichthyismus hystrix, ichthyosis hystrix. (05 Mar 2000) |
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| hyperkeratosis, epidermolytic | A form of congenital ichthyosis inherited as an autosomal dominant trait and characterised by erythroderma and severe hyperkeratosis. It is manifested at birth by blisters followed by the appearance of thickened, horny, verruciform scales over the entire body, but accentuated in flexural areas. (12 Dec 1998) |
| epidermolytic hyperkeratosis | Hyperkeratosis, hypergranulosis, and reticular degeneration in the upper epidermis. Generalised epidermolytic hyperkeratosis is present in bullous congenital ichthyosiform erythroderma. Localised epidermolytic hyperkeratosis may be found in epidermal nevi and benign keratoses. Synonym: porcupine skin. (05 Mar 2000) |
| acanthoma | <tumour> A tumour formed by proliferation of epithelial squamous cells. See: keratoacanthoma. Origin: acantho-+ G. -oma, tumour (05 Mar 2000) |
| acanthoma adenoides cysticum | <tumour> Multiple small benign nodules, occurring mostly on the skin of the face, derived from basal cells of hair follicles enclosing small keratin cysts; frequent autosomal dominant inheritance. Synonym: acanthoma adenoides cysticum, Brooke's tumour, epithelioma adenoides cysticum, hereditary multiple trichoepithelioma. Origin: tricho-+ epithelioma (05 Mar 2000) |
| acanthoma fissuratum | A fissure bordered by acanthosis developing at a site of friction by spectacle frames, usually behind the ears. (05 Mar 2000) |
| clear cell acanthoma | A sharply demarcated benign epidermal lesion of a leg or arm with acanthosis and accumulation of glycogen in keratinocytes having pale staining cytoplasm. (05 Mar 2000) |
| Degos' acanthoma | <tumour> An obsolete term for clear cell acanthoma. (05 Mar 2000) |