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enoyl-CoA hydratase - 3-hydroxyacyl-CoA dehydrogenase - dodecanoyl-coenzyme A delta-isomerase <chemical> Catalyses the second and third reactions of the fatty acid beta-oxidation cycle, converting enoyl-CoA to 3-ketoacyl-CoA; EC 4.2.1.17 and EC 1.1.1.35 and EC 5.3.3.8; consider also multifunctional protein-a
Synonym: peroxisomal bifunctional enzyme, enoyl-coenzyme a hydratase -- 3-hydroxyacyl-coenzyme a dehydrogenase, peroxisomal trifunctional enzyme, delta(3), delta(2)-enoyl-CoA isomerase--2-enoyl-CoA hydratase--3-hydroxyacyl-CoA dehydrogenase
(26 Jun 1999)
enoyl-CoA hydratase <enzyme> An enzyme that catalyses reversibly the hydration of unsaturated fatty acyl-CoA to yield beta-hydroxyacyl-CoA. It plays a role in the oxidation of fatty acids and in mitochondrial fatty acid synthesis, has broad specificity, and is most active with crotonyl-CoA.
Chemical name: (3S)-3-Hydroxyacyl-CoA hydro-lyase
Registry number: EC 4.2.1.17
(12 Dec 1998)
enoyl-CoA reductase acyl-CoA dehydrogenase (NADPH+)
2-enoyl-CoA reductase Acyl-CoA dehydrogenase (NADP+).
(05 Mar 2000)
2-methyl branched-chain enoyl-CoA reductase <enzyme> Important in the reversal of beta-oxidation under anaerobic conditions in ascaris suum
Registry number: EC 1.3.1.52
Synonym: 2-methyl bce-CoA reductase
(26 Jun 1999)
enoyl The acyl radical of an unsaturated aliphatic acid.
Origin: -ene + -oyl
(05 Mar 2000)
enoyl-ACP reductase 1. An enzyme catalyzing hydrogenation of acyl-ACP complexes to 2,3-dehydroacyl-ACP's, with NAD+ as hydrogen acceptor; important in fatty acid metabolism.
Synonym: crotonyl-ACP reductase.
2. A variant enzyme has been found carrying out the same reaction as enoyl-ACP reductase, but with NADP+ as hydrogen acceptor.
Synonym: acyl-ACP dehydrogenase, acyl-ACP reductase.
(05 Mar 2000)
enoyl hydrase <enzyme> An enzyme that catalyses reversibly the hydration of unsaturated fatty acyl-CoA to yield beta-hydroxyacyl-CoA. It plays a role in the oxidation of fatty acids and in mitochondrial fatty acid synthesis, has broad specificity, and is most active with crotonyl-CoA.
Chemical name: (3S)-3-Hydroxyacyl-CoA hydro-lyase
Registry number: EC 4.2.1.17
(12 Dec 1998)
butyryl-CoA acetoacetate CoA transferase <enzyme> Butyryl-CoA + acetoacetate yields butyrate + acetoacetyl-CoA
Registry number: EC 2.8.3.-
Synonym: butyryl-coenzyme a acetoacetate coenzyme a transferase
(26 Jun 1999)
malonyl-CoA-acetyl CoA-acyl carrier protein S-acyltransferase <enzyme> Specific for either malonyl-CoA or acetyl-CoA; a component of fatty acid synthase
Registry number: EC 2.8.3.-
Synonym: mcoa-acoa acp acyltransferase
(26 Jun 1999)
succinyl-CoA-3-hydroxy-3-methylglutarate CoA transferase <enzyme> Rat liver mitochondrial enzyme which catalyses transfer of a conezyme a molecule from succinyl-CoA to 3-hydroxy-3-methylglutarate
Registry number: EC 2.8.3.-
Synonym: succinylcoa-hmg CoA transferase, sca-hmg cat
(26 Jun 1999)
succinyl CoA propionate CoA-transferase <enzyme> Succinyl CoA and propionate gives propionyl CoA and succinate
Registry number: EC 2.8.3.-
Synonym: succinyl coenzyme a propionate coenzyme a-transferase
(26 Jun 1999)
acetate-CoA ligase <enzyme> An enzyme that catalyses the formation of CoA derivatives from ATP, acetate, and CoA to form AMP, pyrophosphate, and acetyl CoA. It acts also on propionates and acrylates.
Chemical name: Acetate:CoA ligase (AMP-forming)
Registry number: EC 6.2.1.1
(12 Dec 1998)
acetate-succinate CoA-transferase <enzyme> Tritichomonas and trichomonas enzyme converts acetyl-CoA and succinate to acetate and succinyl-CoA
Registry number: EC 2.8.3.-
Synonym: acetate-succinate coenzyme a-transferase
(26 Jun 1999)
acetoacetyl-CoA Intermediate in the oxidation of fatty acids and in the formation of ketone bodies; also formed from two molecules of acetyl-CoA; major role is condensation with acetyl-CoA to form the important beta-hydroxy-beta-methylglutaryl-CoA.
Synonym: acetoacetyl-coenzyme A.
(05 Mar 2000)
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