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edrophonium <chemical> A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
Pharmacological action: anti-arrhythmia agents, antidotes, cholinesterase inhibitor, parasympathomimetic.
Chemical name: Benzenaminium, N-ethyl-3-hydroxy-N,N-dimethyl-
(12 Dec 1998)
edrophonium chloride Dimethylethyl (3-hydroxyphenyl)ammonium chloride;a competitive antagonist of skeletal muscle relaxants (curare derivatives and gallamine triethiodide) and an anticholinesterase, used as an antidote for curariform drugs, as a diagnostic agent in myasthenia gravis, and in myasthenic crisis.
(05 Mar 2000)
edrophonium test <investigation> A test used to measure the amount of antibodies to acetylcholine receptors on nerve endings. This is a diagnostic test for myasthenia gravis.
A normal value is no antibodies in the bloodstream. Amyotrophic lateral sclerosis patients may also demonstrate an abnormal edrophonium test result.
(24 Mar 1998)
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