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dynein <protein> Large multimeric protein (600-800 kD) with ATPase activity, constitutes the side arms of the outer microtubule doublets in the ciliary axoneme and is responsible for the sliding. Probably (together with kinesin) involved in microtubule associated movement elsewhere. Cytoplasmic dynein is MAP Ic.
(18 Nov 1997)
dynein arm A structure extending clockwise from one tubule of each of the 9 doublet microtubules toward the adjacent doublet seen in the axoneme of cilia or flagella (including human sperm tails); congenital absence of dynein, reflected structurally by absence of dynein arm's, can account for symptoms seen in Kartagener's syndrome and in immotile cilia syndromes.
(05 Mar 2000)
dynein atpase <enzyme> A structural protein which forms the arms on the microtubule doublets of cilia and flagella. In the presence of divalent cations, dynein catalyses the hydrolysis of ATP. This hydrolysis plays an important functional role in the motility process.
Chemical name: Dynein ATP phosphohydrolase (tubulin-translocating)
Registry number: EC 3.6.1.33
(12 Dec 1998)
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