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radiotherapy dosage The total amount of radiation absorbed by tissues as a result of radiotherapy.
(12 Dec 1998)
gene dosage <molecular biology> Number of copies of a particular gene locus in the genome, in most cases either one or two.
(18 Nov 1997)
gene dosage compensation The putative mechanism that adjusts the X-linked phenotypes of males and females to compensate for the haploid state in males and the diploid state in females. It is now largely ascribed to lyonization which compensates the mean of the dose but not its variance, which is greater in females.
(05 Mar 2000)
gene dosage effect In codominant alleles, the more or less linear relationship between the phenotypic value and the number of genes of one type substituted by another type.
(05 Mar 2000)
dosage The determination and regulation of the size, frequency and number of doses.
(18 Nov 1997)
dosage compensation <genetics> A genetic regulatory mechanism which operates to equalise the phenotypic expression of characteristics determined by genes on the x chromosome so that they are equally expressed in the xy male and the xx female.
(12 Dec 1998)
dosage effect The alteration of a phenotype by an increased dosage, or amount, of the product of the gene.
(09 Oct 1997)
dosage forms Completed forms of the pharmaceutical preparation in which prescribed doses of medication are included. They are designed to resist action by gastric fluids, prevent vomiting and nausea, reduce or alleviate the undesirable taste and smells associated with oral administration, achieve a high concentration of drug at target site, or produce a delayed or long-acting drug effect. They include capsules, liniments, ointments, pharmaceutical solutions, powders, tablets, etc.
(12 Dec 1998)
dosage schedule A scheme set up to determine and regulate size, frequency and number of doses.
(18 Nov 1997)
absorbed dose The amount of energy absorbed per unit mass of irradiated material at the target site; in radiation therapy, the former unit for absorbed dose is the rad; the current (S.I.) unit is the gray.
(05 Mar 2000)
air dose The radiation dose, expressed in roentgens, delivered at a point in free air.
Synonym: air dose.
(05 Mar 2000)
bone marrow dose The cumulative dose to the blood-forming organ from therapeutic or nuclear fallout irradiation; the presumed leukemogenic dose.
(05 Mar 2000)
booster dose A dose given at some time after an initial dose to enhance the effect, said usually of antigens for the production of antibodies.
(05 Mar 2000)
breast dose in mammography <radiology> 180 mrad / view -- mid-breast dose, guideline: less than 1 rad for 2-view exam
(12 Dec 1998)
maintenance dose In chemotherapy, systematic dosage at a level that maintains protection against exacerbation.
(05 Mar 2000)
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