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dl- <prefix> Prefix (in small capital letters) denoting a substance consisting of equal quantities of the two enantiomorphs, d and l; replaces the older dl-(in lower case italics) as a more exact definition of structure.
(05 Mar 2000)
dl-hyoscyamine <drug> A toxic alkaloid extracted from belladonna and other members of thenightshade family, it is typically used to dilate the eye and to stopmuscular spasms.
Pharmacologic action: Parasympatholytic. Competitive blockade of acetylcholine at muscarinic receptors. Increases sinus node automaticity and AV conduction.
Uses: Treat bradycardia, asystole, and AV block
Dose: 0.5 - 1.0 mg for bradycardia every 3 - 5 min to a total dose of 0.04 mg/kg. Doses smaller than 0.5 mg can cause a paradoxical bradycardia due to sympathomimetic effects Typically 3 mg is adequate to completely block vagal effects Atropine is well absorbed via endotracheal route - administer 1-2 mg diluted in 10 mL sterile water or normal saline.
Potential complications: 1. Tachyarrhythmias 2. Exacerbation of myocardial ischemia 3. Low dose may cause paradoxical bradycardia 4. Dry mouth, urinary retention, flushed and hot skin 5. Crosses blood-brain barrier which can cause delirium
Note: The denervated heart will not respond to atropine.
(15 Mar 2000)
dl-narcotine <chemistry> An alkaloid existing in small quantities in opium.
Origin: Gr. Gignwskein to know + E. Opium?.
Source: Websters Dictionary
(01 Mar 1998)
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