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disulphide <chemistry> A binary compound of sulphur containing two atoms of sulphur in each molecule; formerly called disulphuret. Cf. Bisulphide.
Origin: Pref. Di- + sulphide.
Source: Websters Dictionary
(01 Mar 1998)
disulphide bond <chemistry, molecular biology> The S S linkage. A linkage formed between the SH groups of two cysteine moieties either within or between peptide chains.
Each cysteine then becomes a half cystine residue. S S linkages stabilise, but do not determine, secondary structure in proteins. They are easily disrupted by SH groups in an exchange reaction and are not present in cytosolic proteins (cytosol has a high concentration of glutathione that has a free SH residue).
(18 Nov 1997)
disulphide bridge <chemistry> A covalent link made by a cystine residue that joins two polypeptide chains.
(09 Oct 1997)
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