| discoid | Shaped like a disk. Origin: Gr. Diskos = disk (18 Nov 1997) |
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| discoid lupus erythematosus | A form of lupus erythematosus in which cutaneous lesions are present; these commonly appear on the face and are atrophic plaques with erythema, hyperkeratosis, follicular plugging, and telangiectasia; in some instances systemic lupus erythematosis may develop. Synonym: chronic discoid lupus erythematosus. (05 Mar 2000) |
| discoidal cleavage | Meroblastic cleavage limited to the small cap (animal pole) of protoplasm of large-yolked eggs, such as the telolecithal eggs of birds. (05 Mar 2000) |
| discoidin | <protein> A lectin, isolated from the cellular slime mould Dictyostelium discoideum, that has a binding site for carbohydrate residues related to galactose. The lectin, that consists of two distinct species (discoidins I and II), is synthesised as the cells differentiate from vegetative to aggregation phase and was originally thought to be involved in intercellular adhesion, but discoidin I is now thought to be involved in adhesion to the substratum by a mechanism resembling that of fibronectin in animals. (18 Nov 1997) |
| chronic discoid lupus erythematosus | A form of lupus erythematosus in which cutaneous lesions are present; these commonly appear on the face and are atrophic plaques with erythema, hyperkeratosis, follicular plugging, and telangiectasia; in some instances systemic lupus erythematosis may develop. Synonym: chronic discoid lupus erythematosus. (05 Mar 2000) |
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| exudative discoid and lichenoid dermatitis | Disease resembling an exudative form of nummular eczema described in Jewish males with oval lesions on the penis, trunk, and face. Synonym: exudative discoid and lichenoid dermatitis, Sulzberger-Garbe syndrome. (05 Mar 2000) |
| lupus erythematosus, discoid | A chronic form of cutaneous lupus erythematosus (lupus erythematosus, cutaneous) in which the skin lesions mimic those of the systemic form but in which systemic signs are rare. It is characterised by the presence of discoid skin plaques showing varying degrees of oedema, erythema, scaliness, follicular plugging, and skin atrophy. Lesions are surrounded by an elevated erythematous border. The condition typically involves the face and scalp, but widespread dissemination may occur. (12 Dec 1998) |