| disaccharidase |
an enzyme that hydrolyzes disaccharides. In humans, the disaccharidases, comprising the β-glycosidase (lactase–phlorhizin hydrolase) complex, sucrase-isomaltase complex; and trehalase, are located in the brush border membrane of the small intestine, hydrolyzing the oligo- and disaccharides produced after luminal digestion of starches and other dietary carbohydrates. See also under deficiency and see disaccharide intolerance, under intolerance.
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| disaccharidase d. |
less than normal activity of disaccharidases of the intestinal mucosa; it usually denotes a generalized deficiency of all such enzymes secondary to a disorder of the small intestine, which clinically may be manifest only as a deficiency of lactase activity, but is sometimes used to denote deficiency of a single enzyme or enzyme complex, e.g., lactase, sucrase-isomaltase complex, or α,α-trehalase. See also individual enzyme deficiencies and see disaccharide intolerance, under intolerance.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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