| DHFR | DiHydroFolate Reductase |
|---|---|
| DHF | dengue hemorrhagic fever; dihydrofolate; dorsihyperflexion |
| DHFR | dihydrofolate reductase |
| DHFRase | dihydrofolate reductase |
| DHFRP | dihydrofolate reductase pseudogene |
| DHFR | Dihydrofolate reductase |
|---|---|
| hDHFR | human dihydrofolate reductase |
| dihydrofolate monooxygenase | <enzyme> 7,8-dihydrofolate plus 1/2 o2 gives 7,8-dihydropterin-6-aldehyde plus p-aminobenzoylglutamate Registry number: EC 1.13.- (26 Jun 1999) |
|---|---|
| dihydrofolate reductase | <enzyme> An enzyme involved in the biosynthesis of folic acid coenzymes, that transfers hydrogen from NADP to dihydrofolate, yielding tetrahydrofolic acid. Inhibitors can be used as antimicrobial and anticancer drugs. Standard source is liver and the enzyme is used to assay dihydrofolate. (18 Nov 1997) |
| thymidylate synthase-dihydrofolate reductase | <chemical> Bifunctional multienzyme complex purified from leishmania major Synonym: ts-dhfr, dhfr-ts (26 Jun 1999) |
|---|
| dihydrofolate |
an ester or dissociated form of dihydrofolic acid. Abbreviated DHF.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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|---|---|
| dihydrofolate reductase |
[EC 1.5.1.3] an enzyme of the oxidoreductase class that catalyzes the reduction of dihydrofolate to tetrahydrofolate, using NADPH as an electron donor. The reaction produces reduced folate for amino acid metabolism, purine ring synthesis, and the formation of deoxythymidine monophosphate. Methotrexate and other folic acid antagonists used as chemotherapeutic drugs act by inhibiting this enzyme. Deficiency of the enzyme may be a cause of megaloblastic anemia responsive to therapy with reduced forms of folic acid. Abbreviated DHFR.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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