| diffuse infantile familial sclerosis | <radiology> Dysmyelinating disease, autosomal recessive, usually presents by 1 yr, specific enzyme deficiency identified, rapid spontaneous nystagmus, poikilothermia Synonym: Krabbe leukodystrophy (12 Dec 1998) |
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| closed comedo | A comedo with a narrow or obstructed opening on the skin surface; closed comedo's may rupture, producing a low-grade dermal inflammatory reaction. Synonym: whitehead. (05 Mar 2000) |
| comedo | <pathology> A plug of keratin and sebum within the dilated orifice of a hair follicle, frequently containing the bacteria Propionibacterium acnes, Staphylococcus albus and Pityrosporon ovale, also called blackhead. See: acne. (18 Nov 1997) |
| open comedo | A comedo with a wide opening on the skin surface capped with a melanin-containing blackened mass of epithelial debris. Synonym: blackhead. (05 Mar 2000) |
| cerebral sclerosis, diffuse | Diffuse progressive degeneration of the white matter of the brain, accompanied by mental deterioration, severe motor disturbances, and early death. (12 Dec 1998) |
| goiter, diffuse toxic | Graves' disease, the most common cause of hyperthroidism, too much thyroid hormone. (12 Dec 1998) |
| chronic diffuse sclerosing osteomyelitis | A proliferative reaction of bone to a low-grade infection of the jaws; most often seen in middle-aged or older black women as extensive, often bilateral radio-opacities of the mandible and maxilla. (05 Mar 2000) |
| hyperostosis, diffuse idiopathic skeletal | A disease of elderly men characterised by large osteophytes that bridge vertebrae and ossification of ligaments and tendon insertions. (12 Dec 1998) |
| diffuse | Not definitely limited or localised, widely distributed. Origin: L. Dis = apart, fundere = to pour (18 Nov 1997) |
| diffuse abdominal calcification | <radiology> Ovarian cystadenocarcinoma (psammomatous Calcium), pseudomyxoma peritonei, pseudomucinous cystadenoma of ovary, mucocele of appendix, undifferentiated abdominal malignancy, TB peritonitis, oil granulomata, meconium peritonitis (12 Dec 1998) |
| diffuse abscess | A collection of pus not circumscribed by a well-defined capsule. (05 Mar 2000) |
| diffuse aneurysm | An aneurysm that has enlarged and spread to the surrounding tissues in consequence of rupture of its walls. Synonym: consecutive aneurysm. (05 Mar 2000) |
| diffuse angiokeratoma | <disease> Lysosomal storage disease caused by a deficiency of alpha-galactosidase a and resulting in an accumulation of globotriaosylceramide in the renal and cardiovascular systems. The disease is characterised by telangiectatic skin lesions, renal failure, and disturbances of the cardiovascular, gastrointestinal, and central nervous systems. Inheritance: x-linked. (08 Mar 2000) |
| diffuse arterial ectasia | Spontaneous enlargement with dilation of the vessels in a circumscribed area. (05 Mar 2000) |
| diffuse brain atrophy | A form of dementia caused by destruction (atrophy) of the frontal lobes of the brain. This condition leads to the progressive deterioration of mental functioning. Incidence: 9 in 10,000 people in the general population. (27 Sep 1997) |