| radiation damage, bulk | <radiobiology> General term describing changes in chemical and/or metallurgical properties of structure components of fusion reactor caused by atomic displacement and nuclear transmutation events occuring as a result of exposure to a radiation environment (such as the neutrons emitted from a fission or D-T fusion reactor). (09 Oct 1997) |
|---|---|
| radiation damage, surface | <radiobiology> General term describing damage to the surface of the containment structure which directly interfaces with the thermonuclear plasma, includes such phenomena as radiation blistering, charged-particle (or neutron) sputtering, and spallation or exfoliation of layers of the surface. (09 Oct 1997) |
| mitochondrial oxidative damage endonuclease | <enzyme> An 8-oxog-specific DNA endonuclease from rat liver mitochondria; recognises and incises at 8-oxog and abasic acid sites in duplex DNA Registry number: EC 3.1.25.- Synonym: oxidative damage-specific endonuclease, mtode enzyme (26 Jun 1999) |
| damage | 1. Injury or harm to person, property, or reputation; an inflicted loss of value; detriment; hurt; mischief. "He that sendeth a message by the hand of a fool cutteth off the feet and drinketh damage." (Prov. Xxvi. 6) "Great errors and absurdities many commit for want of a friend to tell them of them, to the great damage both of their fame and fortune." (Bacon) 2. The estimated reparation in money for detriment or injury sustained; a compensation, recompense, or satisfaction to one party, for a wrong or injury actually done to him by another. In common-law action, the jury are the proper judges of damages. Consequential damage. See Consequential. Exemplary damages, those given for a violation of a right where no actual loss has accrued. Vindictive damages, those given specially for the punishment of the wrongdoer. Synonym: Mischief, injury, harm, hurt, detriment, evil, ill. See Mischief. Origin: OF. Damage, domage, F. Dommage, fr. Assumed LL. Damnaticum, from L. Damnum damage. See Damn. To ocassion damage to the soudness, goodness, or value of; to hurt; to injure; to impair. "He . . . Came up to the English admiral and gave him a broadside, with which he killed many of his men and damaged the ship." (Clarendon) Origin: Cf. OF. Damagier, domagier. See Damage. Source: Websters Dictionary (01 Mar 1998) |
| DNA damage | Drug- or radiation-induced injuries in DNA that introduce deviations from its normal double-helical conformation. These changes include structural distortions which interfere with replication and transcription, as well as point mutations which disrupt base pairs and exert damaging effects on future generations through changes in DNA sequence. If the damage is minor, it can often be repaired (DNA repair). If the damage is extensive, it can induce apoptosis. (12 Dec 1998) |
| cerebral sclerosis, diffuse | Diffuse progressive degeneration of the white matter of the brain, accompanied by mental deterioration, severe motor disturbances, and early death. (12 Dec 1998) |
| goiter, diffuse toxic | Graves' disease, the most common cause of hyperthroidism, too much thyroid hormone. (12 Dec 1998) |
| chronic diffuse sclerosing osteomyelitis | A proliferative reaction of bone to a low-grade infection of the jaws; most often seen in middle-aged or older black women as extensive, often bilateral radio-opacities of the mandible and maxilla. (05 Mar 2000) |
| hyperostosis, diffuse idiopathic skeletal | A disease of elderly men characterised by large osteophytes that bridge vertebrae and ossification of ligaments and tendon insertions. (12 Dec 1998) |
| diffuse | Not definitely limited or localised, widely distributed. Origin: L. Dis = apart, fundere = to pour (18 Nov 1997) |
| diffuse abdominal calcification | <radiology> Ovarian cystadenocarcinoma (psammomatous Calcium), pseudomyxoma peritonei, pseudomucinous cystadenoma of ovary, mucocele of appendix, undifferentiated abdominal malignancy, TB peritonitis, oil granulomata, meconium peritonitis (12 Dec 1998) |
| diffuse abscess | A collection of pus not circumscribed by a well-defined capsule. (05 Mar 2000) |
| diffuse aneurysm | An aneurysm that has enlarged and spread to the surrounding tissues in consequence of rupture of its walls. Synonym: consecutive aneurysm. (05 Mar 2000) |
| diffuse angiokeratoma | <disease> Lysosomal storage disease caused by a deficiency of alpha-galactosidase a and resulting in an accumulation of globotriaosylceramide in the renal and cardiovascular systems. The disease is characterised by telangiectatic skin lesions, renal failure, and disturbances of the cardiovascular, gastrointestinal, and central nervous systems. Inheritance: x-linked. (08 Mar 2000) |
| diffuse arterial ectasia | Spontaneous enlargement with dilation of the vessels in a circumscribed area. (05 Mar 2000) |