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  • degradation senile
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FDP fibrin degradation product; fibrinogen degradation product; flexor digitorum profundus; frontodextra...
PD Doctor of Pharmacy; Dublin Pharmacopoeia; interpupillary distance; Paget disease; pancreatic duct; p...
NIDS nonionic detergent soluble
FDP(s)   1) Fibrinolytic split Products(= FSP)
  2) Fibrinogen Degradation Products
BGD blood group degradation
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ADF Acid Detergent Fiber
DRM Detergent resistant membranes
NDF Neutral detergent fiber
NDF Neutral detergent fibre
SD Solvent detergent
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  • marginal degradation
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anionic detergent Detergents in which the hydrophilic funtion is fulfilled by an anionic grouping. Fatty acids are the best known natural products in this class, but it is doubtful if they have a specific detergent function in any biological system. The important synthetic species are aliphatic sulphate esters, for example sodium dodecyl sulphate (SDS or SLS).
(18 Nov 1997)
nonionic detergent <chemistry> Detergent in which the hydrophilic head group is uncharged. In practice hydrophilicity is usually conferred by OH groups.
Examples are the polyoxyethylene p t octyl phenols known as Tritons and octyl glucoside. Nonionic detergents can be used to solubilise intrinsic membrane proteins with less tendency to denature them than charged detergents. They do not usually cause disassembly of structures such as microfilaments and microtubules that depend on protein protein interactions.
(18 Nov 1997)
degradation <biochemistry, chemistry> The reduction of a chemical compound to one less complex, as by splitting off one or more groups.
(18 Nov 1997)
detergent <chemistry> An agent which purifies or cleanses.
<cell biology> Amphipathic, surface active, molecules with polar (water soluble) and nonpolar hydrophobic) domains. They bind strongly to hydrophobic molecules or molecular domains to confer water solubility.
Examples include: sodium dodecyl sulphate, fatty acid salts, the Triton family, octyl glycoside.
Origin: L. Detergere = to cleanse
(18 Nov 1997)
edman degradation A lab technique used to find out the order of amino acids in a polypeptide (chain of amino acids). It involves using the Edman reagent, phenyl isothiocyanate (PITC), to react one by one with each amino acid, in order. The technique is used in machines which automatically sequence (determine the order of subunits) polypeptides.
(09 Oct 1997)
zwitterionic detergent Detergents that are zwitterionic; often used as surfactants and in the release of proteins from biomembranes.
Synonym: zwitterionic detergent.
Origin: zwitterion + detergent
(05 Mar 2000)
fibrin degradation products <haematology, investigation> A test that measures fibrin degradation products which result from the dissolution of a blood clot.
Normal value is less than 10 mcg/ml (micrograms per millilitre).
They may be increased in conditions such as burns, placental abruption, heart disease, DIC, after massive blood transfusion, hypoxia, intrauterine foetal death, portacaval shunt, leukaemia, transfusion reaction, transplant rejection, sepsis, renal failure and preeclampsia.
Acronym: FDP
(23 Sep 2002)
fibrin fibrinogen degradation products <chemical> Soluble protein fragments formed by the proteolytic action of plasmin on fibrin or fibrinogen. Fdp and their complexes profoundly impair the haemostatic process and are a major cause of haemorrhage in intravascular coagulation and fibrinolysis.
Pharmacological action: antithrombins.
(12 Dec 1998)
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