| depressive syndrome | 1. A lowering or decrease of functional activity. 2. <psychiatry> A mental state of depressed mood characterised by feelings of sadness, despair and discouragement. Depression ranges from normal feelings of the blues through dysthymia to major depression. It in many ways resembles the grief and mourning that follow bereavement, there are often feelings of low self esteem, guilt and self reproach, withdrawal from interpersonal contact and somatic symptoms such as eating and sleep disturbances. Origin: L. Depremere = to press down (18 Nov 1997) |
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| manic-depressive | 1. Pertaining to a manic-depressive psychosis (bipolar disorder). 2. One suffering from such a disorder. (05 Mar 2000) |
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| manic-depressive disease | See manic-depression. (12 Dec 1998) |
| manic-depressive disorder | An obsolete term for one of the mood disorders; i.e., bipolar disorder, depression; affective psychosis, affective disorder, bipolar disorder, and endogenous depression. (05 Mar 2000) |
| manic-depressive illness | Now referred to as bipolar illness, characterised by the occurrence of mania (euphoria) alternating with bouts of depression. (27 Sep 1997) |
| manic-depressive psychosis | Perviously referred to as manic depressive illness, characterised by the occurrence of mania (euphoria) alternating with bouts of depression. (27 Sep 1997) |
| depressive | 1. Pushing down. 2. Pertaining to or causing depression. (05 Mar 2000) |
| depressive disorder | An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent. (12 Dec 1998) |
| depressive neurosis | See: depression, dysthymia. (05 Mar 2000) |
| depressive psychosis | A major disorder of mood in which biologic factors are believed to play a prominent role. See: depression. (05 Mar 2000) |
| depressive reaction | 1. A lowering or decrease of functional activity. 2. <psychiatry> A mental state of depressed mood characterised by feelings of sadness, despair and discouragement. Depression ranges from normal feelings of the blues through dysthymia to major depression. It in many ways resembles the grief and mourning that follow bereavement, there are often feelings of low self esteem, guilt and self reproach, withdrawal from interpersonal contact and somatic symptoms such as eating and sleep disturbances. Origin: L. Depremere = to press down (18 Nov 1997) |
| depressive stupor | A stuporous syndrome from which recovery is the rule, as opposed to malignant stupor. Synonym: depressive stupor. (05 Mar 2000) |
| disease, manic-depressive | See Manic-depression. (12 Dec 1998) |
| Aarskog-Scott syndrome | A syndrome of ocular hypertelorism, anteverted nostrils, broad upper lip, saddle-bag scrotum, and laxity of ligaments resulting in genu recurvatum, flat feet, and hyperextensible fingers; X-linked and autosomal dominant forms. Synonym: Aarskog-Scott syndrome. (05 Mar 2000) |
| Aarskog syndrome | <syndrome> Grier et al. (1983) reported father and 2 sons with typical Aarskog syndrome, including short stature, hypertelorism, and shawl scrotum. They tabulated the findings in 82 previous cases. X-linked recessive inheritance has been repeatedly suggested. The family reported by Welch (1974) had affected males in 3 consecutive generations. Thus, there is either genetic heterogeneity or this is an autosomal dominant with strong sex-influence and possibly ascertainment bias resulting from use of the shawl scrotum as a main criterion. Stretchable skin was present in the cases of Grier et al. (1983). Teebi et al. (1993) reported the case of an affected mother and 4 sons (including a pair of monozygotic twins) by 2 different husbands. They suggested that the manifestations were as severe in the mother as in the sons and that this suggested autosomal dominant inheritance. Actually, the mother seemed less severely affected, compatible with X-linked inheritance. Clinical signs: Mild to moderate short stature,normocephaly, Widow's peak hair, maxillary hypoplasia, broad nasal bridge, anteverted nostrils, long philtrum, broad upper lip, curved linear dimple below the lower lip, hypertelorism, ptosis, down-slanted palpebral fissures, ophthalmoplegia, strabismus, hyperopic astigmatism, large cornea, floppy ears, lop-ears,cleft lip/palate, shawl scrotum, saddle-bag scrotum, cryptorchidism, brachydactyly, digital contractures, clinodactyly, mild syndactyly, transverse palmar crease, lymphoedema of the feet, ligamentous laxity, osteochondritis dissecans, proximal finger joint hyperextensibility, flexed distal finger joints, genu recurvatum, flat feet, stretchable skin, cervical spine hypermobility, odontoid anomaly, macrocytic anaemia, hemochromatosis, hepatomegaly, portal cirrhosis, imperforate anus, rectoperineal fistula, interstitial pulmonary disease, sternal deformity. Inheritance: Sex-influenced autosomal dominant form, also X-linked form. (05 Aug 1998) |
| abdominal muscle deficiency syndrome | <syndrome> Congenital absence (partial or complete) of abdominal muscles, in which the outline of the intestines is visible through the protruding abdominal wall; in males, genitourinary anomalies (urinary tract dilation and cryptorchidism) are also found; genetics unclear. (05 Mar 2000) |