| deoxy sugar | A sugar containing fewer oxygen atoms than carbon atoms and in which, consequently, one or more carbons in the molecule lack an attached hydroxyl group. Synonym: desoxy sugar. (05 Mar 2000) |
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| deoxy- | <prefix> Prefix to chemical names of substances to indicate replacement of an -OH by an H. The older desoxy-has been retained in some instances. (05 Mar 2000) |
| deoxyadenine nucleotides | Adenine nucleotides which contain deoxyribose as the sugar moiety. (12 Dec 1998) |
| deoxyadenosine | 2'-Deoxyribosyladenine, one of the four major nucleosides of DNA (the others being deoxycytidine, deoxyguanosine, and thymidine). The 5' derivative is also an important component of one form of vitamin B12. Deoxyadenosine accumulates in individuals with severe combined immunodeficiency disease. (05 Mar 2000) |
| deoxyadenosine methylase | <enzyme> An enzyme responsible for the methylation of adenine residues in specific sequences. Synonym: deoxyadenosine methylase. (05 Mar 2000) |
| deoxyadenosines | Adenosine molecules which can be substituted in any position, but are lacking one hydroxyl group in the ribose part of the molecule. (12 Dec 1998) |
| deoxyadenylic acid | Deoxyadenosine monophosphate, a hydrolysis product of DNA, differing from adenylic acid in containing deoxyribose in place of ribose. Synonym: adenine deoxyribonucleotide. (05 Mar 2000) |
| deoxybarbiturate | A barbiturate compound lacking the oxygen atom at the #2 position in the ring; example of a deoxybarbiturate is the antiepileptic drug, primidone. See: barbiturate. (05 Mar 2000) |
| deoxycholate | <biochemistry> A bile salt. The sodium salt is used as a detergent to make membrane proteins water soluble. (18 Nov 1997) |
| deoxycholic acid | <chemical> (3 alpha,5 beta,12 alpha)-3,12-dihydroxy-5-cholan-24-oic acid. A bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent to solubilise fats for intestinal absorption, is reabsorbed itself, and is used as a choleretic and detergent. Pharmacological action: cholagogues and choleretics. Chemical name: Cholan-24-oic acid, 3,12-dihydroxy-, (3alpha,5beta,12alpha)- (12 Dec 1998) |
| deoxycholoyl-CoA synthetase | <enzyme> Catalyses the synthesis of deoxycholoyl-CoA from deoxycholic acid in rat liver Registry number: EC 6.2.1.- Synonym: deoxycholic acid CoA ligase, deoxycholate CoA ligase, deoxycholoyl-coenzyme a synthetase (26 Jun 1999) |
| deoxycoformycin | A purine analog which acts as an antimetabolite; potent inhibitor of adenosine deaminase. Used as an antineoplastic agent. See: pentostatin. (05 Mar 2000) |
| deoxycorticosterone | 11-Deoxycorticosterone; 21-hydroxypregn-4-ene-3,20-dione;an adrenocortical steroid, principally a biosynthetic precursor of corticosterone and possibly aldosterone, that rarely appears in adrenocortical secretions; a potent mineralocorticoid with no appreciable glucocorticoid activity. Synonym: 21-hydroxyprogesterone, cortexone, deoxycortone, desoxycortone. Deoxycorticosterone acetate, desoxycorticosterone acetate;acetate salt used for intramuscular injection for replacement therapy of the adrenocortical steroid. Deoxycorticosterone pivalate, desoxycorticosterone pivalate;pivalate salt of the steroid. (05 Mar 2000) |
| deoxycortone | 11-Deoxycorticosterone; 21-hydroxypregn-4-ene-3,20-dione;an adrenocortical steroid, principally a biosynthetic precursor of corticosterone and possibly aldosterone, that rarely appears in adrenocortical secretions; a potent mineralocorticoid with no appreciable glucocorticoid activity. Synonym: 21-hydroxyprogesterone, cortexone, deoxycortone, desoxycortone. Deoxycorticosterone acetate, desoxycorticosterone acetate;acetate salt used for intramuscular injection for replacement therapy of the adrenocortical steroid. Deoxycorticosterone pivalate, desoxycorticosterone pivalate;pivalate salt of the steroid. (05 Mar 2000) |
| deoxycytidine | <chemical> Chemical name: Cytidine, 2'-deoxy- (12 Dec 1998) |
| CDP-4-keto-6-deoxy-D-glucose-3-dehydrase | <enzyme> A pyridoxamine 5'-phosphate (pmp) dependent enzyme which catalyses the deoxygenation step in 3,6-dideoxyhexose synthesis, in which the c-3 hydroxyl group of the cdp-4-keto-6-deoxy-d-hexose intermediate is replaced by a hydrogen atom; isolated from yersinia pseudotuberculosis Registry number: EC 4.2.1.- Synonym: ckdg dehydrase, cytidine diphosphate-4-keto-6-deoxy-d-glucose-3-dehydrase, cdp-6-deoxy-l-threo-d-glycero-4-hexulose 3-dehydrase (26 Jun 1999) |
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| CDP-6-deoxy-4-hexulose-3-dehydrase reductase | <enzyme> Nadh-dependent enzyme that transfer of electrons to cdp-6-deoxy-l-threo-d-glycero-4-hexulose 3-dehydrase, which catalyses reduction of cdp-6-deoxy-delta(3,4)-glucoseen to cdp-4-keto-3,6-dideoxy-d-glucose Registry number: EC 1.3.1.- Synonym: ckdg dehydrase reductase, cdp--6-deoxy-l-threo-d-glycero-4-hexulose-3-dehydrase reductase (26 Jun 1999) |
| CDP-6-deoxy-delta(3,4)-glucoseen reductase | <enzyme> Key enzyme catalyzing the biosynthetic formation of cdp-ascarylose via a pyridoxamine-linked intermediate; the enzyme can also oxidise NADPH in the presence of oxygen; from yerisinia pseudotuberculosis Registry number: EC 1.17.1.- Synonym: cddg reductase (26 Jun 1999) |
| phospho-2-keto-3-deoxy-gluconate aldolase | <enzyme> Minor descriptor (75-84); on-line and index medicus search aldehyde-lyases (75-84) Registry number: EC 4.1.2.14 Synonym: 2-keto-3-deoxy-6-phosphogluconate aldolase, 6-phospho-2-keto-3-deoxy-d-gluconate d-glyceraldehyde-3-phosphate-lyase, kdpga (26 Jun 1999) |
| 2-amino-2-deoxy-D-galactose | <chemical> Chemical name: D-Galactose, 2-amino-2-deoxy- (12 Dec 1998) |
| 2-deoxy-scyllo-inosose synthase | <enzyme> Responsible for the formation of 2-deoxy-scyllo-inosose from d-glucose; exhibits close similarity to dehydroquinate synthase; not clear whether it catalyses only the oxidoreduction of c-4 and/or the intramolecular cyclization between c-1 and c-6 Registry number: EC 4.99.- Synonym: 2-deoxy-scyllo-inosose synthetase (26 Jun 1999) |
| 2-keto-3-deoxy-D-galactonate aldolase | <enzyme> Involved in the non-phosphorolytic d-galactonate catabolism in fungi; cleaves 2-keto-3-deoxy-d-galactonate to pyruvate and glyceraldehyde Registry number: EC 4.1.2.- Synonym: kdgal aldolase (26 Jun 1999) |
| 2-keto-3-deoxy-L-pentonate aldolase | <enzyme> Chemical name: 2-keto-3-deoxy-l-arabonate aldolase Registry number: EC 4.1.2.18 Synonym: 3-deoxy-d-pentulosonic acid aldolase, 2-keto-3-deoxy-d-xylonate aldolase (26 Jun 1999) |
| 3-deoxy-D-glycero-2,5-hexodiulosonate dehydrogenase | <enzyme> Forms 2-keto-3-deoxy-d-gluconate from 3-deoxy-d-glycero-2,5-hexodiulosonate; uses NADH Registry number: EC 1.1.1.127 Synonym: 2-keto-3-deoxygluconate oxidoreductase, ketodeoxyuronate dehydrogenase, 2-dehydro-3-deoxy-d-gluconate 5-dehydrogenase NADP+ (26 Jun 1999) |
| 3-deoxy-manno-octulosonate-8-phosphatase | <enzyme> Kdo-8-phosphate yields kdo + inorganic phosphate Registry number: EC 3.1.3.45 Synonym: 2-keto-3-deoxyoctonate-8-phosphate phosphatase, kdo-8-phosphatase, 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase (26 Jun 1999) |
| 3-deoxy-manno-octulosonate cytidyltransferase | <enzyme> Catalyzed the formation of cmp-kdo from ctp and kdo; k-cks is encoded by kpsu and participates in k5 polysaccharide expression Registry number: EC 2.7.7.38 Synonym: cmp-kdo synthetase, ctp-cmp-3-deoxy-d-manno-octulosonate cytidylyltransferase, k-cks synthetase, kpsu gene product, kdsb gene product (26 Jun 1999) |
| 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase | <enzyme> Converts 5-keto-4-deoxyuronate to 2,5-diketo-3-deoxygluconate Registry number: EC 5.3.1.17 Synonym: 5-keto-4-deoxyuronate isomerase (26 Jun 1999) |
| 6-phospho-2-keto-3-deoxy-galactonate aldolase | <enzyme> Chemical name: 2-keto-3-deoxygalactonate 6-p aldolase Registry number: EC 4.1.2.21 Synonym: 2-keto-3-deoxygalactonate-6-phosphate aldolase (26 Jun 1999) |