| acute demyelinating polyneuropathy | <neurology> A neurologic condition. Synonym: Guillain-Barre syndrome. Origin: Gr. Pathos = disease (27 Sep 1997) |
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| chronic inflammatory demyelinating polyneuropathy | An uncommon, acquired, demyelinating sensorimotor polyneuropathy, clinically characterised by insidious onset, and slow evolution, (either steady progression or stepwise), and chronic course; symmetrical weakness is a predominant symptom, often involving proximal leg muscles, accompanied by paresthesias, but not pain; CSF examination shows elevated protein, while electrodiagnostic studies reveal evidence of a demyelinating process, primarily conduction slowing rather than block; sometimes responds to prednisone. (05 Mar 2000) |
| segmental demyelinating polyneuropathy | A type of polyneuropathy in which almost solely the peripheral nerve myelin is affected; can be both familial (e.g., Charcot-Marie Tooth disease, type 1), or acquired (e.g., Guillain-Barre syndrome); on motor nerve conduction studies, manifested as conduction slowing or block. Synonym: segmental demyelinating polyneuropathy. (05 Mar 2000) |
| demyelinating disease | Diseases in which the myelin sheath of nerves is destroyed and that often have an autoimmune component. Examples are multiple sclerosis, acute disseminated encephalomyelitis (a complication of acute viral infection), experimental allergic encephalomyelitis, Guillain-Barre syndrome. (18 Nov 1997) |
| demyelinating diseases | Any condition characterised by the destruction of myelin and extensive loss of the myelin sheaths of the nerve fibres. It affects both the central and peripheral nervous systems. Its aetiology is at present unknown. (12 Dec 1998) |
| demyelinating encephalopathy | Extensive idiopathic loss of myelin sheaths in the brain, as occurs in leukodystrophy. (05 Mar 2000) |
| demyelinating polyneuropathy | A type of polyneuropathy in which almost solely the peripheral nerve myelin is affected; can be both familial (e.g., Charcot-Marie Tooth disease, type 1), or acquired (e.g., Guillain-Barre syndrome); on motor nerve conduction studies, manifested as conduction slowing or block. Synonym: segmental demyelinating polyneuropathy. (05 Mar 2000) |
| acute haemorrhagic encephalitis | Encephalitis of apoplectoid character due to blood extravasation. Synonym: encephalitis haemorrhagica. (05 Mar 2000) |
| acute inclusion body encephalitis | The most common acute encephalitis, caused by HSV-1; affects persons of any age; preferentially involves the inferomedial portions of the temporal lobe and the orbital portions of the frontal lobes; pathologically, severe haemorrhagic necrosis is present along with, in the acute stages, intranuclear eosinophilic inclusion bodies in the neurons and glial cells. Synonym: acute inclusion body encephalitis, herpes encephalitis. (05 Mar 2000) |
| acute necrotizing encephalitis | An acute form of encephalitis, characterised by destruction of brain parenchyme. (05 Mar 2000) |
| arthritis-encephalitis virus, caprine | A species of lentivirus, subgenus ovine-caprine lentiviruses (lentiviruses, ovine-caprine), closely related to visna-maedi virus and causing acute encephalomyelitis, chronic arthritis, pneumonia, mastitis, and glomerulonephritis in goats. It is transmitted mainly in the colostrum and milk. (12 Dec 1998) |
| Australian X encephalitis | A severe encephalitis with a high mortality rate occurring in the Murray Valley of Australia; the disease is most severe in children and is characterised by headache, fever, malaise, drowsiness or convulsions, and rigidity of the neck; extensive brain damage may result; it is caused by the Murray Valley encephalitis virus (genus Flavivirus). Synonym: Australian X disease, Australian X encephalitis. (05 Mar 2000) |
| bacterial encephalitis | Encephalitis of bacterial aetiology. Synonym: encephalitis pyogenica, purulent encephalitis, suppurative encephalitis. (05 Mar 2000) |
| bovine spongiform encephalitis | <pathology> A neuro-degenerative disease found in domestic cattle which is related to a number of other similar diseases found in other animal species, including humans. The most well-known of these other diseases are scrapie, found in sheep, and Creutzfeldt-Jakob Disease, found in humans. The family of diseases is caused by an abnormally-configured protein called a prion. The function of the protein in its normal configuration is not certain. The diseases are similar to Alzheimer's disease in humans, except the progressive loss of brain function is more rapid. (09 Oct 1997) |
| bunyavirus encephalitis | Encephalitis of abrupt onset, with severe frontal headache and low-grade to moderate fever, caused by members of the genus Bunyavirus (Bunyaviridae family); infections also occur in rodents, lagomorphs, and domestic animals. Synonym: California encephalitis. (05 Mar 2000) |