| delayed hypersensitivity r. |
a reaction of cell-mediated immunity, named in contrast to immediate hypersensitivity reactions because its onset is 24 to 72 hours after the antigenic challenge; the term is usually used to denote the subset of type IV hypersensitivity reactions (Gell and Coombs classification) involving cytokine release and macrophage activation, as opposed to direct cytolysis, but can be used more broadly, even sometimes being used synonymously with type IV hypersensitivity r. The classic delayed hypersensitivity reaction is the tuberculin reaction observed in skin testing.
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| delayed hypersensitivity reaction |
A localized skin response mediated by T cells, which occurs 24 to 72 hr after injection of a specific antigen to which the person has been previously sensitized. It is used routinely to screen for tuberculosis i
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