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definitive callus The callus which has become converted into osseous tissue.
Synonym: permanent callus.
(05 Mar 2000)
definitive erythroblast <haematology, pathology> Embryonic erythroblast found in the liver, smaller than primitive erythroblasts, they lose their nucleus at the end of the maturation cycle and produce erythrocytes with adult haemoglobin.
(18 Nov 1997)
definitive host <epidemiology> The host in which a parasite reproduces sexually.
(05 Dec 1998)
definitive lysosomes Lysosome's in which lysis takes place, owing to the activity of hydrolytic enzymes; they are believed to eventually become residual bodies.
Synonym: definitive lysosomes, digestive vacuole.
(05 Mar 2000)
definitive method An analytical procedure for the measurement of a specified analyte in a specified material which is known to give essentially the true value for the concentration of the analyte.
(05 Mar 2000)
definitive prosthesis A dental prosthesis to be used over a prescribed period of time.
(05 Mar 2000)
acceptor site The ribosomal binding site for the aminoacyl-tRNA during protein synthesis.
(05 Mar 2000)
acceptor splicing site Boundary between the right end of an intron and the left end of the adjacent exon.
Synonym: acceptor splicing site.
(05 Mar 2000)
active site <chemistry> A specific region of an enzyme where a substrate binds and catalysis takes place (binding site).
(06 May 1997)
allosteric site A specific site on a multi-subunit enzyme or other protein that is not the substrate binding site, but that when reversibly bound by an effector, induces a conformational change in the protein, altering its catalytic or binding properties.
(12 Dec 1998)
amidation site <molecular biology> A C terminus consensus sequence, required for C terminus amidation of peptides. Consensus is glycine, followed by 2 basic amino acids (arg or lys).
(18 Nov 1997)
antibody combining site <immunology> In immune network theory, an idiotope, an antigenic site of an antibody that is responsible for that antibody binding to an antigenic determinant (epitope).
Also used of the site on a ligand molecule to which a cell surface receptor binds.
(18 Nov 1997)
antigen-binding site <immunology> In immune network theory, an idiotope, an antigenic site of an antibody that is responsible for that antibody binding to an antigenic determinant (epitope).
Also used of the site on a ligand molecule to which a cell surface receptor binds.
(18 Nov 1997)
antigen-combining site See: paratope.
(05 Mar 2000)
apurinic site <molecular biology> Sites in DNA from which purines have been lost by cleavage of the deoxy ribose N glycosidic linkage.
(18 Nov 1997)
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