| defective virus | <virology> A virus genetically deficient in replication, but that may nevertheless be replicated when it co-infects a host cell in the presence of a wild type helper virus. most acute transforming retroviruses are defective, since their acquisition of oncogenes seems to be accompanied by deletion of essential viral genetic information. (18 Nov 1997) |
|---|---|
| defective viruses | Viruses which lack a complete genome so that they cannot completely replicate or cannot form a protein coat. Some are host-dependent defectives, meaning they can replicate only in cell systems which provide the particular genetic function which they lack. Others, called satellite viruses, are able to replicate only when their genetic defect is complemented by a helper virus. (12 Dec 1998) |
| ventral nervous system defective | <molecular biology> A Drosophila gene encoding an integral membrane glycoprotein related to amyloidogenic glycoprotein. (12 Jan 1998) |
|---|---|
| defective | Denoting or exhibiting a defect; imperfect; a failure of quality. (05 Mar 2000) |
| defective bacteriophage | A temperate bacteriophage mutant whose genome does not contain all of the normal components and cannot become fully infectious virus, yet can replicate indefinitely in the bacterial genome as defective probacteriophage; many defective bacteriophage's are mediators of transduction. Synonym: defective phage. (05 Mar 2000) |
| defective interfering particle | An incomplete virus that is unable to replicate and interferes with replication of an infectious virus. (05 Mar 2000) |
| defective organism | Mutant with a nutritional requirement not present in the wild type organism. Synonym: defective organism, deficiency mutant. (05 Mar 2000) |
| defective phage | A temperate bacteriophage mutant whose genome does not contain all of the normal components and cannot become fully infectious virus, yet can replicate indefinitely in the bacterial genome as defective probacteriophage; many defective bacteriophage's are mediators of transduction. Synonym: defective phage. (05 Mar 2000) |
| defective probacteriophage | See: defective bacteriophage. (05 Mar 2000) |
| defective prophage | A temperate bacteriophage mutant whose genome does not contain all of the normal components and cannot become fully infectious virus, yet can replicate indefinitely in the bacterial genome as defective probacteriophage; many defective bacteriophage's are mediators of transduction. Synonym: defective phage. (05 Mar 2000) |
| bovine virus diarrhoea virus | A virus of the genus Pestivirus, in the family Togaviridae, causing bovine virus diarrhoea; New York, Oregon, and Indiana strains of the virus are recognised. Synonym: mucosal disease virus. (05 Mar 2000) |
| abelson leukaemia virus | A defective murine leukaemia virus capable of transforming lymphoid cells and producing a rapidly progressing lymphoid leukaemia after superinfection with friend, moloney, or rauscher virus. (12 Dec 1998) |
| Abelson murine leukaemia virus | A retrovirus belonging to the Type C retrovirus group subfamily (family Oncovirinae) which is associated with leukaemia and produces in vitro transformation of mouse cells. (05 Mar 2000) |
| adeno-associated virus | <virology> A genus of viruses in the family Parvoviridae which are all defective viruses (unable to replicate by themselves) and depend on the co-infection of their host cell by other, nondefective viruses to help them replicate. (09 Oct 1997) |
| adenoidal-pharyngeal-conjunctival virus | <virology> An icosahedral (20-sided) virus that contains DNA, there are over 40 different adenovirus varieties, some of which cause the common cold. (10 May 1997) |
| adenosatellite virus | <virology> A genus of viruses in the family Parvoviridae which are all defective viruses (unable to replicate by themselves) and depend on the co-infection of their host cell by other, nondefective viruses to help them replicate. (09 Oct 1997) |
| african horse sickness virus | A species of orbivirus that causes disease in horses, mules, and donkeys. (12 Dec 1998) |