| cystine disease | Lysosomal storage disorders of unknown molecular defect, characterised by widespread deposition of cystine crystals in reticuloendothelial cells. (12 Dec 1998) |
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| cystine storage disease | Lysosomal storage disorders of unknown molecular defect, characterised by widespread deposition of cystine crystals in reticuloendothelial cells. (12 Dec 1998) |
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| meso-cystine | An isomer of cystine in which the configuration about one of the alpha-carbons is d, about the other, l, so that the molecule as a whole possesses a plane of symmetry and is optically inactive. Note that meso-cystine is not dl-cystine. Dl-cystine is a racaemic mixture of dd-cystine and ll-cystine. (05 Mar 2000) |
| half cystine | Refers to one-half of a cystine molecule or of a cystinyl residue in a protein or peptide. (05 Mar 2000) |
| cystine | <amino acid> The amino acid formed by linking two cysteine residues with a disulphide linkage between the two SH groups. The analagous compound present within proteins is termed two half cysteines. (18 Nov 1997) |
| cystine bridge | A disulfide linkage between two cysteinyl residues in a poly-or oligopeptide or in a protein, any disulfide linkage between any thiol-containing moieties of a larger molecule. Synonym: cystine bridge. (05 Mar 2000) |
| cystine calculus | A calculus composed of cystine, soft and faintly radiopaque. (05 Mar 2000) |
| cystine desulfhydrase | <enzyme> A multifunctional pyridoxal phosphate enzyme. In the final step in the biosynthesis of cysteine it catalyses the cleavage of cystathionine to yield cysteine, ammonia, and 2-ketobutyrate. Chemical name: L-Cystathionine cysteine-lyase (deaminating) Registry number: EC 4.4.1.1 (12 Dec 1998) |
| cystine lyase | <enzyme> An enzyme catalyzing the hydrolysis of l-cystathionine to pyruvate, l-homocysteine, and NH3. See: cystathionine gamma-lyase. Synonym: beta-cystathionase, cystine lyase. (05 Mar 2000) |
| L-cysteine-cystine C-S lyase | <enzyme> C-des - cysteine desulfhydrase; a pyridoxal phosphate- containing enzyme from synechocystis involved information of fe-s cluster of ferredoxin; catalyses the breakdown of l-cysteine to yield sulfide, pyruvate and ammonia; increased activity with cystine, yielding cysteine persulfide as the primary product; mw about 43 kD Registry number: EC 4.4.1.- Synonym: c-des lyase (26 Jun 1999) |
| aaa disease | Endemic anaemia of ancient Egypt, ascribed in the Papyrus Ebers to intestinal infestation with ancylostoma; now called ancylostomiasis. (05 Mar 2000) |
| ABO haemolytic disease of the newborn | Erythroblastosis foetalis due to maternal-foetal incompatibility with respect to an antigen of the ABO blood group; the foetus possesses A or B antigen which is lacking in the mother, and the mother produces immune antibody which causes haemolysis of foetal erythrocytes. (05 Mar 2000) |
| accumulation disease | A disease characterised by abnormal accumulation of a metabolic product in certain cells and tissues; examples include the mucopolysaccharidoses, lipoidoses. (05 Mar 2000) |
| Acosta's disease | A condition that results from prolonged exposure to high altitude. Symptoms include a continuous dry cough, shortness of breath, poor exercise tolerance, dizziness, headache, sleep difficulty, anorexia, confusion, fatigue and a rapid pulse. Treatment includes the immediate movement to a lower altitude. Prophylaxis has been accomplished successfully with the use of acetazolamide (Diamox). (27 Sep 1997) |
| acquired immunodeficiency disease | Acquired immunodeficiency disease: Disease caused by infection with the human immunodeficiency virus (HIV). (12 Dec 1998) |
| acute disease | Disease having a short and relatively severe course. (12 Dec 1998) |